HitPredict

Interactor 1: CACO2 (Q13137)
Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52)
Gene: CALCOCO2

Interactor 2: MLP3C (Q9BXW4)
Microtubule-associated protein 1 light chain 3 gamma (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (Microtubule-associated proteins 1A/1B light chain 3C) (MAP1A/MAP1B LC3 C) (MAP1A/MAP1B light chain 3 C)
Gene: MAP1LC3C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.751

The method score is based on:

Property Details
Experiments 26451915, 32296183, 33723372, 25771791, 30679426, 23022382, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, x-ray crystallography, anti tag coimmunoprecipitation, nuclear magnetic resonance, fluorescence polarization spectroscopy, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000421 - autophagosome membrane
GO:0005776 - autophagosome
GO:0005829 - cytosol
GO:0031410 - cytoplasmic vesicle
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 446
Hs

1 147
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025