HitPredict

Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: CALI (Q13939)
Calicin
Gene: CCIN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 588
+	Hs
		1096281 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		KLH20_HUMAN (404-585): 1.01e-30: 128: 9.78
+	Dm
		877798 RB27C_DROME (99-400): 4.25e-73: 236: 28.17		KELC_DROME (124-585): 2.13e-39: 156: 10.65
+	Hs
		1096056 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		KLH17_HUMAN (425-585): 1.61e-25: 113: 11.66
+	Dm
		877817 RB27C_DROME (99-400): 4.25e-73: 236: 28.17		Q9VK21_DROME (124-585): 1.5e-33: 137: 9.75
+	Hs
		1096171 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		KLH32_HUMAN (8-403): 4.14e-20: 96.3: 23.53
+	Hs
		1096097 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		KLH36_HUMAN (422-584): 9.23e-19: 92.2: 10.59
+	Hs
		1102093 PABP4_HUMAN (98-275): 1.57e-37: 146: 18.92		GAN_HUMAN (6-403): 7.84e-21: 98.6: 21.48
+	Dm
		462182 ROA1_DROME (179-271): 1.98e-16: 82.1: 24.24		KELC_DROME (124-585): 2.13e-39: 156: 10.65
+	Hs
		1431651 PABP3_HUMAN (2-382): 7.79e-31: 126: 16.41		GAN_HUMAN (6-403): 7.84e-21: 98.6: 21.48
+	Hs
		550463 PABP1_HUMAN (181-270): 2.86e-10: 64: 20.62		GAN_HUMAN (6-403): 7.84e-21: 98.6: 21.48