HitPredict

Interactor 1: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Interactor 2: LONF2 (Q1L5Z9)
LON peptidase N-terminal domain and RING finger protein 2 (Neuroblastoma apoptosis-related protease) (RING finger protein 192)
Gene: LONRF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.50	0.579

Property	Details
Experiments	37474791, 32814053
Identification Methods	affinity chromatography technology, pull down, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 754
+	Hs
		731248 TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00		STIP1_HUMAN (20-459): 4.25e-29: 124: 10.10
+	Hs
		172025 HNRDL_HUMAN (62-376): 5.65e-71: 231: 23.60		STIP1_HUMAN (20-459): 4.25e-29: 124: 10.10
+	Hs
		731109 ROA3_HUMAN (98-269): 2.35e-69: 225: 28.57		STIP1_HUMAN (20-459): 4.25e-29: 124: 10.10
+	Hs
		171955 HNRDL_HUMAN (62-376): 5.65e-71: 231: 23.60		OGT1_HUMAN (166-359): 1.08e-17: 89.9: 11.34
+	Mm
		1295901 ROA3_MOUSE (98-269): 2.41e-69: 225: 28.57		BFAR_MOUSE (421-526): 2.47e-12: 71.8: 26.85
+	Hs
		185658 PABP4_HUMAN (98-275): 1.57e-37: 146: 18.92		OGT1_HUMAN (166-359): 1.08e-17: 89.9: 11.34
+	Hs
		731278 HNRPD_HUMAN (81-238): 5.61e-21: 95.1: 35.93		STIP1_HUMAN (20-459): 4.25e-29: 124: 10.10
+	Hs
		550139 PABP1_HUMAN (181-270): 2.86e-10: 64: 20.62		STIP1_HUMAN (20-459): 4.25e-29: 124: 10.10
+	Hs
		185686 HNRPD_HUMAN (81-238): 5.61e-21: 95.1: 35.93		OGT1_HUMAN (166-359): 1.08e-17: 89.9: 11.34
+	Hs
		185388 PABP1_HUMAN (181-270): 2.86e-10: 64: 20.62		OGT1_HUMAN (166-359): 1.08e-17: 89.9: 11.34