Interactor 1: STAT (Q24151)
Signal transducer and transcription activator (d-STAT) (Protein marelle)
Gene: Stat92E

Interactor 2: JAK (Q24592)
Tyrosine-protein kinase hopscotch (EC 2.7.10.2)
Gene: hop

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.713

The method score is based on:

Property Details
Experiments 27194748, unassigned4
Identification Methods affinity chromatography technology, experimental interaction detection
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2
Common GO terms GO:0005126 - cytokine receptor binding
GO:0005829 - cytosol
GO:0007259 - cell surface receptor signaling pathway via JAK-STAT
GO:0007298 - border follicle cell migration
GO:0007350 - blastoderm segmentation
and 14 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 761
Dm

1 1177
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024