HitPredict

Interactor 1: SLY1 (Q24179)
Protein sly1 homolog
Gene: Slh

Interactor 2: Q9VR90 (Q9VR90)
Syntaxin 16
Gene: Syx16

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SNARE~Sec1
Common GO terms	GO:0000139 - Golgi membrane GO:0000149 - SNARE binding GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Dm			1 352
+	Dm
		1096639 SLY1_DROME (1-639): 0: 615: 100.00		STX1A_DROME (30-351): 3.14e-54: 181: 15.64
+	Dm
		1096638 SLY1_DROME (1-639): 0: 615: 100.00		STX5_DROME (1-334): 6.22e-52: 180: 16.37
+	At
		1338394 SLY1_ARATH (2-639): 0: 541: 38.32		SYP32_ARATH (2-350): 1.59e-67: 217: 16.10
+	Hs
		152168 SCFD1_HUMAN (3-631): 0: 559: 56.90		STX16_HUMAN (1-330): 1.04e-57: 191: 34.38
+	Hs
		1027531 SCFD1_HUMAN (3-631): 0: 559: 56.90		STX5_HUMAN (1-333): 1.69e-49: 171: 16.47
+	Hs
		1017732 SCFD1_HUMAN (3-631): 0: 559: 56.90		STX4_HUMAN (13-350): 4.35e-48: 165: 14.75
+	Hs
		178695 SCFD1_HUMAN (3-631): 0: 559: 56.90		STX7_HUMAN (94-352): 1.3e-45: 158: 21.46
+	Dm
		1096641 SLY1_DROME (1-639): 0: 615: 100.00		Q7K0X9_DROME (103-350): 2.06e-20: 91.5: 21.43
+	Dm
		1096657 SLY1_DROME (1-639): 0: 615: 100.00		Q9VU45_DROME (216-352): 3.98e-14: 73.8: 25.00
+	Mm
		192851 STXB2_MOUSE (21-634): 8.57e-165: 486: 17.27		STX1A_MOUSE (27-352): 7.25e-57: 188: 16.56
+	Hs
		699262 STXB2_HUMAN (21-633): 2.04e-161: 477: 17.45		STX2_HUMAN (41-350): 1.03e-56: 188: 14.52
+	Rn
		699178 STXB2_RAT (21-633): 6.11e-160: 473: 17.27		STX1A_RAT (27-352): 9.27e-57: 188: 16.56
+	Sp
		142035 SLY1_SCHPO (3-629): 1.03e-166: 492: 35.32		SED5_SCHPO (1-348): 6.28e-48: 165: 15.23
+	At
		1319858 KEULE_ARATH (7-631): 9.43e-162: 480: 18.91		SY121_ARATH (77-332): 1.6e-49: 171: 16.60
+	Mm
		936823 STXB2_MOUSE (21-634): 8.57e-165: 486: 17.27		STX4_MOUSE (13-350): 5.2e-47: 163: 14.45
+	Rn
		838510 STXB2_RAT (21-633): 6.11e-160: 473: 17.27		STX2_RAT (27-332): 1.11e-51: 175: 13.07
+	Hs
		119613 STXB3_HUMAN (27-630): 6.52e-154: 458: 16.88		STX2_HUMAN (41-350): 1.03e-56: 188: 14.52
+	Dm
		991124 ROP_DROME (24-631): 1.7e-154: 459: 18.20		STX1A_DROME (30-351): 3.14e-54: 181: 15.64
+	Hs
		119633 STXB3_HUMAN (27-630): 6.52e-154: 458: 16.88		STX4_HUMAN (13-350): 4.35e-48: 165: 14.75
+	Mm
		936822 STXB3_MOUSE (28-631): 3.3e-154: 458: 17.01		STX4_MOUSE (13-350): 5.2e-47: 163: 14.45