HitPredict

Interactor 1: RFA4 (Q13156)
Replication protein A 30 kDa subunit (RP-A p30) (Replication factor A protein 4) (RF-A protein 4)
Gene: RPA4

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0000781 - chromosome, telomeric region GO:0005654 - nucleoplasm GO:0006260 - DNA replication GO:0006281 - DNA repair and 1 others more... GO:0006289 - nucleotide-excision repair
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 1834
+	Hs
		854025 RFA4_HUMAN (1-261): 1.83e-106: 310: 100.00		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		588131 RFA2_HUMAN (1-261): 7.67e-105: 306: 42.03		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		588983 RFA2_HUMAN (1-261): 7.67e-105: 306: 42.03		SRCAP_HUMAN (982-1802): 3.8e-21: 104: 10.50
+	Hs
		588699 RFA2_HUMAN (1-261): 7.67e-105: 306: 42.03		MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56
+	Hs
		588146 RFA2_HUMAN (1-261): 7.67e-105: 306: 42.03		MAP1B_HUMAN (819-1706): 3.35e-10: 67.8: 10.90
+	Hs
		161405 RFA2_HUMAN (1-261): 7.67e-105: 306: 42.03		KMT2D_HUMAN (769-1409): 5.92e-09: 63.6: 9.52