HitPredict

Interactor 1: RUXF (Q24297)
Small nuclear ribonucleoprotein F (snRNP-F) (Membrane-associated protein Deb-B) (Sm protein F) (Sm-F) (SmF)
Gene: SmF

Interactor 2: Q9VJI7 (Q9VJI7)
GEO08441p1 (Like Sm 7, isoform A) (Like Sm 7, isoform B) (Like Sm 7, isoform C) (RH73529p)
Gene: LSm7

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0071011 - precatalytic spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 88 Dm			1 110
+	Dm
		1368675 Q9VKW8_DROME (9-82): 1.16e-32: 112: 29.33		Q9VJI7_DROME (1-110): 5.99e-39: 127: 100.00
+	Hs
		1356296 LSM4_HUMAN (9-82): 2.84e-33: 113: 29.33		LSM7_HUMAN (13-110): 5.95e-34: 114: 76.53
+	Hs
		911992 RUXF_HUMAN (5-77): 4.96e-32: 108: 82.19		LSM7_HUMAN (13-110): 5.95e-34: 114: 76.53
+	At
		1340905 LSM6A_ARATH (3-84): 6.11e-32: 108: 40.24		LSM7_ARATH (17-109): 1.31e-32: 111: 61.29
+	Hs
		912211 LSM4_HUMAN (9-82): 2.84e-33: 113: 29.33		LSM3_HUMAN (1-96): 2.86e-25: 92.7: 27.72
+	Hs
		928049 LSM4_HUMAN (9-82): 2.84e-33: 113: 29.33		RSMN_HUMAN (24-95): 1.04e-23: 92.7: 27.40
+	Dm
		1097032 RUXF_DROME (1-88): 1.23e-36: 120: 100.00		Q9W087_DROME (24-108): 2.96e-22: 85: 23.53
+	Hs
		539204 LSM4_HUMAN (9-82): 2.84e-33: 113: 29.33		RSMB_HUMAN (24-95): 2.4e-23: 91.5: 27.40
+	At
		1228011 LSM6A_ARATH (3-84): 6.11e-32: 108: 40.24		LSM1B_ARATH (23-106): 4.88e-26: 95.4: 28.57
+	Hs
		911791 RUXF_HUMAN (5-77): 4.96e-32: 108: 82.19		LSM3_HUMAN (1-96): 2.86e-25: 92.7: 27.72
+	Hs
		911801 RUXF_HUMAN (5-77): 4.96e-32: 108: 82.19		RSMN_HUMAN (24-95): 1.04e-23: 92.7: 27.40
+	Hs
		321444 LSM4_HUMAN (9-82): 2.84e-33: 113: 29.33		LSM8_HUMAN (24-107): 4.09e-23: 87.3: 28.57
+	Hs
		538890 RUXF_HUMAN (5-77): 4.96e-32: 108: 82.19		RSMB_HUMAN (24-95): 2.4e-23: 91.5: 27.40
+	Hs
		167728 LSM4_HUMAN (9-82): 2.84e-33: 113: 29.33		LSM1_HUMAN (23-109): 3.21e-22: 85.7: 26.44
+	Dm
		1213197 Q9VKW8_DROME (9-82): 1.16e-32: 112: 29.33		Q8IMX8_DROME (1-96): 1.15e-22: 86.1: 24.75
+	Hs
		911790 RUXF_HUMAN (5-77): 4.96e-32: 108: 82.19		RUXG_HUMAN (18-100): 2.34e-24: 89.6: 32.53
+	Dm
		1369698 Q9VKW8_DROME (9-82): 1.16e-32: 112: 29.33		Q9W087_DROME (24-108): 2.96e-22: 85: 23.53
+	Hs
		321386 RUXF_HUMAN (5-77): 4.96e-32: 108: 82.19		LSM8_HUMAN (24-107): 4.09e-23: 87.3: 28.57
+	Hs
		167678 RUXF_HUMAN (5-77): 4.96e-32: 108: 82.19		LSM1_HUMAN (23-109): 3.21e-22: 85.7: 26.44
+	Hs
		68408 RUXF_HUMAN (5-77): 4.96e-32: 108: 82.19		RUXGL_HUMAN (18-100): 3.57e-22: 84.2: 31.33