Protein: PRX1
Peroxiredoxin PRX1, mitochondrial (Prx) (EC 1.11.1.25) (EC 1.11.1.27) (1-Cys PRX) (Glutaredoxin-dependent peroxiredoxin) (Glutathione-dependent peroxiredoxin) (Mitochondrial thiol peroxidase) (mTPx) (Thioredoxin peroxidase)

Gene: PRX1
Organism: Saccharomyces cerevisiae S288C
Interactions: 43
UniProt ID: P34227

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0008379 - thioredoxin peroxidase activity
GO:0034599 - cellular response to oxidative stress
GO:0045454 - cell redox homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

757957

PRX1
Peroxiredoxin PRX1, mitochondrial

3

14

Small-scale

0.862

High

757959

SRX1
Sulfiredoxin

2

5

Small-scale

0.767

High

673329

TRX3
Thioredoxin-3, mitochondrial

1

20

Small-scale

0.618

High

740488

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

2

4

High-throughput

0.588

High

726911

HS104
Heat shock protein 104

2

3

Small-scale

0.584

High

752088

HSP78
Heat shock protein 78, mitochondrial

2

3

High-throughput

0.584

High

757970

SSK2
MAP kinase kinase kinase SSK2

1

2

High-throughput

0.536

High

554584

RM02
Large ribosomal subunit protein bL27m

1

0

Small-scale

0.513

High

736229

RM41
Large ribosomal subunit protein uL23m

1

0

Small-scale

0.513

High

736325

RM49
Large ribosomal subunit protein mL61

1

0

Small-scale

0.513

High

757961

RM04
Large ribosomal subunit protein uL29m

1

0

Small-scale

0.513

High

757962

RM36
Large ribosomal subunit protein bL31m

1

0

Small-scale

0.513

High

757963

RM40
Large ribosomal subunit protein uL24m

1

0

Small-scale

0.513

High

692324

KCC1
Calcium/calmodulin-dependent protein kinase I

1

1

High-throughput

0.501

High

416876

CDC25
Cell division control protein 25

1

0

High-throughput

0.480

High

510360

HSP77
Import motor subunit, mitochondrial

1

7

High-throughput

0.479

High

579146

HSC82
ATP-dependent molecular chaperone HSC82

1

6

High-throughput

0.479

High

604935

MDHM
Malate dehydrogenase, mitochondrial

1

7

Small-scale

0.479

High

635950

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

4

High-throughput

0.479

High

679545

CDC48
Cell division control protein 48

1

8

High-throughput

0.479

High

757969

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

757971

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

757972

GLRX5
Monothiol glutaredoxin-5, mitochondrial

1

1

High-throughput

0.479

High

697323

COQ8
Atypical kinase COQ8, mitochondrial

1

0

High-throughput

0.458

High

746785

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

757960

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.458

High

757965

BCA1
Branched-chain-amino-acid aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

757966

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

757973

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

602394

PHO85
Cyclin-dependent protein kinase PHO85

1

10

High-throughput

0.457

High

656738

KC12
Casein kinase I homolog 2

1

2

High-throughput

0.457

High

735478

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

7

High-throughput

0.457

High

757958

HSL1
Probable serine/threonine-protein kinase HSL1

1

4

High-throughput

0.457

High

757964

KSP1
Serine/threonine-protein kinase KSP1

1

3

High-throughput

0.457

High

544370

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

741295

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

757967

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

706700

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

757968

PAC11
WD repeat-containing protein PAC11

1

0

High-throughput

0.279

Low

748322

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

757974

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

757975

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025