Protein: PACE1
Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3)

Gene: PACE1, SCYL3
Organism: Homo sapiens
Interactions: 174
UniProt ID: Q8IZE3

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

582873

EZRI
Ezrin

3

5

Small-scale

0.861

High

187379

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

2

2

High-throughput

0.776

High

976402

RB11A
Ras-related protein Rab-11A

2

6

High-throughput

0.754

High

1316288

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

11

High-throughput

0.698

High

170226

AURKA
Aurora kinase A

1

19

High-throughput

0.691

High

953554

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.691

High

959358

RAP1B
Ras-related protein Rap-1b

1

13

High-throughput

0.691

High

1148307

CNN3
Calponin-3

1

2

High-throughput

0.691

High

1316282

SRPK1
SRSF protein kinase 1

1

16

High-throughput

0.691

High

1316292

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

3

3

High-throughput

0.675

High

1316283

THIOM
Thioredoxin, mitochondrial

4

1

High-throughput

0.637

High

773559

COPB2
Coatomer subunit beta'

2

3

High-throughput

0.628

High

921947

COPA
Coatomer subunit alpha

2

3

High-throughput

0.628

High

1316314

COPG2
Coatomer subunit gamma-2

2

10

High-throughput

0.628

High

1316320

COPG1
Coatomer subunit gamma-1

2

10

High-throughput

0.628

High

374042

RASN
GTPase NRas

1

16

High-throughput

0.618

High

484180

PGFRB
Platelet-derived growth factor receptor beta

1

6

High-throughput

0.618

High

631335

RAB5A
Ras-related protein Rab-5A

1

9

High-throughput

0.618

High

901379

RAB7A
Ras-related protein Rab-7a

1

10

High-throughput

0.618

High

901927

RAB9A
Ras-related protein Rab-9A

1

11

High-throughput

0.618

High

945040

RAB25
Ras-related protein Rab-25

1

6

High-throughput

0.618

High

1235295

STYK1
Tyrosine-protein kinase STYK1

1

13

High-throughput

0.618

High

327350

ZFPL1
Zinc finger protein-like 1

2

4

High-throughput

0.611

High

952239

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

2

3

High-throughput

0.606

High

333088

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

5

High-throughput

0.601

High

873261

COPD
Coatomer subunit delta

2

2

High-throughput

0.601

High

1316264

TGFA1
Transforming growth factor-beta receptor-associated protein 1

2

8

High-throughput

0.601

High

163136

CHK1
Serine/threonine-protein kinase Chk1

1

10

High-throughput

0.575

High

296523

STAM2
Signal transducing adapter molecule 2

1

4

High-throughput

0.575

High

318996

MICA2
[F-actin]-monooxygenase MICAL2

1

3

High-throughput

0.575

High

876927

KC1A
Casein kinase I isoform alpha

1

12

High-throughput

0.575

High

1316278

SCYL1
N-terminal kinase-like protein

1

18

High-throughput

0.575

High

1316291

RGAP1
Rac GTPase-activating protein 1

1

4

High-throughput

0.575

High

630879

RAB4A
Ras-related protein Rab-4A

1

8

High-throughput

0.553

High

158253

COPE
Coatomer subunit epsilon

1

1

High-throughput

0.536

High

216271

PPIH
Peptidyl-prolyl cis-trans isomerase H

1

2

High-throughput

0.536

High

964026

COPZ1
Coatomer subunit zeta-1

1

2

High-throughput

0.536

High

1025722

PURA
Transcriptional activator protein Pur-alpha

1

2

High-throughput

0.536

High

1118301

EXOS2
Exosome complex component RRP4

1

1

High-throughput

0.536

High

1208368

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

1

3

High-throughput

0.536

High

1316263

DDX54
ATP-dependent RNA helicase DDX54

1

4

High-throughput

0.536

High

1229359

LHX8
LIM/homeobox protein Lhx8

1

2

High-throughput

0.523

High

431852

ITB1
Integrin beta-1

1

3

High-throughput

0.515

High

1316259

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.514

High

334209

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.513

High

568674

GYS1
Glycogen [starch] synthase, muscle

1

0

High-throughput

0.513

High

874050

TPC10
Trafficking protein particle complex subunit 10

1

0

High-throughput

0.513

High

1316273

SYAP1
Synapse-associated protein 1

1

0

High-throughput

0.513

High

1316275

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.513

High

1316280

VMA22
Vacuolar ATPase assembly protein VMA22

1

0

High-throughput

0.513

High

1316302

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.513

High

651088

RFX1
MHC class II regulatory factor RFX1

1

3

High-throughput

0.489

High

1123037

FHL2
Four and a half LIM domains protein 2

1

1

High-throughput

0.489

High

1316267

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

1

High-throughput

0.489

High

1316276

HDA11
Histone deacetylase 11

1

7

High-throughput

0.489

High

1316293

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

2

High-throughput

0.489

High

1316298

JPH1
Junctophilin-1

1

1

High-throughput

0.489

High

1316307

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

1

High-throughput

0.489

High

1316321

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.489

High

139925

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

4

High-throughput

0.479

High

173051

XPO1
Exportin-1

1

13

High-throughput

0.479

High

179964

BET1
BET1 homolog

1

5

High-throughput

0.479

High

218441

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

226121

STX6
Syntaxin-6

1

5

High-throughput

0.479

High

604086

CXA1
Gap junction alpha-1 protein

1

9

High-throughput

0.479

High

827226

ARL1
ADP-ribosylation factor-like protein 1

1

6

High-throughput

0.479

High

896577

VASP
Vasodilator-stimulated phosphoprotein

1

3

High-throughput

0.479

High

939940

TPTE
Putative tyrosine-protein phosphatase TPTE

1

5

High-throughput

0.479

High

958148

ARP3
Actin-related protein 3

1

5

High-throughput

0.479

High

1004124

CXAR
Coxsackievirus and adenovirus receptor

1

2

High-throughput

0.479

High

1041165

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

1156146

ZYX
Zyxin

1

4

High-throughput

0.479

High

1233337

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

1276208

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

1316271

GOGA1
Golgin subfamily A member 1

1

2

High-throughput

0.479

High

1316304

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.479

High

1316313

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

2

High-throughput

0.479

High

1316269

JPH3
Junctophilin-3

1

1

High-throughput

0.470

High

1316279

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

1316297

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1316309

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

1316312

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

48691

ESYT2
Extended synaptotagmin-2

1

5

High-throughput

0.445

High

60371

NBAS
NBAS subunit of NRZ tethering complex

1

1

High-throughput

0.445

High

104348

F5H6I7
Atlastin GTPase 3

1

5

High-throughput

0.445

High

211815

ZW10
Centromere/kinetochore protein zw10 homolog

1

1

High-throughput

0.445

High

213623

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

1

High-throughput

0.445

High

215597

EMC8
ER membrane protein complex subunit 8

1

1

High-throughput

0.445

High

275531

RTN2
Reticulon-2

1

5

High-throughput

0.445

High

283298

ERLN1
Erlin-1

1

1

High-throughput

0.445

High

328948

RTN3
Reticulon-3

1

5

High-throughput

0.445

High

360035

NB5R3
NADH-cytochrome b5 reductase 3

1

1

High-throughput

0.445

High

462512

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

3

High-throughput

0.445

High

535283

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.445

High

567022

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

2

High-throughput

0.445

High

697947

CALR
Calreticulin

1

4

High-throughput

0.445

High

698866

CALX
Calnexin

1

4

High-throughput

0.445

High

814826

CUX1
Homeobox protein cut-like 1

1

4

High-throughput

0.445

High

883112

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

1

High-throughput

0.445

High

888915

TMEDA
Transmembrane emp24 domain-containing protein 10

1

5

High-throughput

0.445

High

903730

SSRD
Translocon-associated protein subunit delta

1

1

High-throughput

0.445

High

904001

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.445

High

921713

COPB
Coatomer subunit beta

1

8

High-throughput

0.445

High

987106

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

5

High-throughput

0.445

High

1009853

NUCB2
Nucleobindin-2

1

1

High-throughput

0.445

High

1015058

ARF5
ADP-ribosylation factor 5

1

5

High-throughput

0.445

High

1027073

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.445

High

1096997

PRDX4
Peroxiredoxin-4

1

2

High-throughput

0.445

High

1131312

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.445

High

1136264

EMC2
ER membrane protein complex subunit 2

1

3

High-throughput

0.445

High

1139217

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

1

High-throughput

0.445

High

1139340

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

1

High-throughput

0.445

High

1145616

RCN1
Reticulocalbin-1

1

4

High-throughput

0.445

High

1146573

TMED2
Transmembrane emp24 domain-containing protein 2

1

5

High-throughput

0.445

High

1147789

DHC24
Delta(24)-sterol reductase

1

3

High-throughput

0.445

High

1152815

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

2

High-throughput

0.445

High

1199207

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

6

High-throughput

0.445

High

1248622

LCLT1
Lysocardiolipin acyltransferase 1

1

4

High-throughput

0.445

High

1258774

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

3

High-throughput

0.445

High

1316256

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

1

High-throughput

0.445

High

1316258

DHB11
Estradiol 17-beta-dehydrogenase 11

1

5

High-throughput

0.445

High

1316260

VP37A
Vacuolar protein sorting-associated protein 37A

1

1

High-throughput

0.445

High

1316261

ATLA2
Atlastin-2

1

5

High-throughput

0.445

High

1316262

MCFD2
Multiple coagulation factor deficiency protein 2

1

1

High-throughput

0.445

High

1316266

SCFD1
Sec1 family domain-containing protein 1

1

4

High-throughput

0.445

High

1316268

ATLA1
Atlastin-1

1

5

High-throughput

0.445

High

1316272

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.445

High

1316274

ASTRA
Protein Aster-A

1

1

High-throughput

0.445

High

1316281

NUDC1
NudC domain-containing protein 1

1

3

High-throughput

0.445

High

1316284

PXL2A
Peroxiredoxin-like 2A

1

1

High-throughput

0.445

High

1316286

ESYT1
Extended synaptotagmin-1

1

5

High-throughput

0.445

High

1316287

NDC1
Nucleoporin NDC1

1

1

High-throughput

0.445

High

1316289

WDR11
WD repeat-containing protein 11

1

1

High-throughput

0.445

High

1316290

LNP
Endoplasmic reticulum junction formation protein lunapark

1

1

High-throughput

0.445

High

1316295

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

1

High-throughput

0.445

High

1316301

RTN4
Reticulon-4

1

5

High-throughput

0.445

High

1316303

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

High-throughput

0.445

High

1316305

TM38B
Trimeric intracellular cation channel type B

1

1

High-throughput

0.445

High

1316310

TECR
Very-long-chain enoyl-CoA reductase

1

1

High-throughput

0.445

High

1316311

VAPA
Vesicle-associated membrane protein-associated protein A

1

5

High-throughput

0.445

High

1316317

TMED5
Transmembrane emp24 domain-containing protein 5

1

5

High-throughput

0.445

High

1316319

SERC
Phosphoserine aminotransferase

1

1

High-throughput

0.445

High

189693

STX7
Syntaxin-7

1

5

High-throughput

0.437

High

1159744

OCLN
Occludin

1

2

High-throughput

0.437

High

1293063

TMM17
Transmembrane protein 17

1

4

High-throughput

0.437

High

1316254

CXD3
Gap junction delta-3 protein

1

9

High-throughput

0.437

High

1316270

ESR2
Estrogen receptor beta

1

12

High-throughput

0.437

High

1316294

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.437

High

591327

CD44
CD44 antigen

1

1

Small-scale

0.428

High

788320

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

0

High-throughput

0.426

High

1248366

UQCC3
Ubiquinol-cytochrome-c reductase complex assembly factor 3

1

0

High-throughput

0.426

High

1271328

MON1B
Vacuolar fusion protein MON1 homolog B

1

0

High-throughput

0.426

High

1316265

BRK1
Protein BRICK1

1

0

High-throughput

0.426

High

50614

HACL2
2-hydroxyacyl-CoA lyase 2

1

1

High-throughput

0.407

High

1316257

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.407

High

1316285

ERP44
Endoplasmic reticulum resident protein 44

1

2

High-throughput

0.407

High

1316296

TMX1
Thioredoxin-related transmembrane protein 1

1

4

High-throughput

0.407

High

1316299

APMAP
Adipocyte plasma membrane-associated protein

1

1

High-throughput

0.407

High

1316306

GPTC2
G patch domain-containing protein 2

1

1

High-throughput

0.407

High

1316308

PSD3
PH and SEC7 domain-containing protein 3

1

2

High-throughput

0.407

High

1316316

DHRS7
Dehydrogenase/reductase SDR family member 7

1

3

High-throughput

0.407

High

1316318

TCAF1
TRPM8 channel-associated factor 1

2

0

High-throughput

0.316

High

1233758

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.313

High

462789

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.279

Low

471668

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.279

Low

554813

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

841213

CNDD3
Condensin-2 complex subunit D3

1

0

High-throughput

0.279

Low

932343

ARSF
Arylsulfatase F

1

0

High-throughput

0.279

Low

1316255

SRBD1
S1 RNA-binding domain-containing protein 1

1

0

High-throughput

0.279

Low

1316277

TRM2B
tRNA

1

0

High-throughput

0.279

Low

1316300

SSF1
Suppressor of SWI4 1 homolog

1

0

High-throughput

0.279

Low

1316315

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

577987

QCR7
Cytochrome b-c1 complex subunit 7

1

0

High-throughput

0.232

Low

1017789

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025