HitPredict

Interactor 1: DIAP1 (Q24306)
Death-associated inhibitor of apoptosis 1 (EC 2.3.2.27) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread) (RING-type E3 ubiquitin transferase Diap1)
Gene: DIAP1

Interactor 2: Q9Y165 (Q9Y165)
BcDNA.GH02435 (F box/ubiquitin conjugase) (Modifier of rpr and grim, ubiquitously expressed)
Gene: morgue

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	12021772, 12021768
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0000209 - protein polyubiquitination GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 438 Dm			1 491
+	Dm
		1097056 DIAP1_DROME (1-438): 9.76e-155: 447: 100.00		Q86NX0_DROME (101-491): 0: 599: 99.74
+	Dm
		639392 DIAP1_DROME (1-438): 9.76e-155: 447: 100.00		UBCD1_DROME (337-484): 9.75e-76: 236: 45.27
+	Hs
		919707 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		UB2D2_HUMAN (337-484): 1.25e-76: 238: 44.60
+	Hs
		957802 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		UB2D4_HUMAN (337-484): 1.21e-76: 238: 45.27
+	Hs
		849308 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		UB2D1_HUMAN (337-484): 1.96e-75: 235: 42.57
+	Hs
		895777 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		UB2D3_HUMAN (337-484): 1.86e-75: 235: 43.24
+	Hs
		851802 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		UB2E1_HUMAN (310-484): 6.38e-74: 233: 33.71
+	Hs
		919817 BIRC7_HUMAN (12-207): 8.87e-38: 140: 21.11		UB2D2_HUMAN (337-484): 1.25e-76: 238: 44.60
+	Hs
		849400 BIRC7_HUMAN (12-207): 8.87e-38: 140: 21.11		UB2D1_HUMAN (337-484): 1.96e-75: 235: 42.57
+	Hs
		895871 BIRC7_HUMAN (12-207): 8.87e-38: 140: 21.11		UB2D3_HUMAN (337-484): 1.86e-75: 235: 43.24
+	Hs
		849456 BIRC6_HUMAN (37-154): 2.35e-34: 138: 32.28		UB2D1_HUMAN (337-484): 1.96e-75: 235: 42.57
+	Hs
		851864 BIRC7_HUMAN (12-207): 8.87e-38: 140: 21.11		UB2E1_HUMAN (310-484): 6.38e-74: 233: 33.71
+	Hs
		957765 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		UB2E2_HUMAN (318-484): 1.25e-71: 227: 34.73
+	Hs
		919831 BIRC8_HUMAN (41-155): 2.84e-34: 129: 24.35		UB2D2_HUMAN (337-484): 1.25e-76: 238: 44.60
+	Hs
		849413 BIRC8_HUMAN (41-155): 2.84e-34: 129: 24.35		UB2D1_HUMAN (337-484): 1.96e-75: 235: 42.57
+	Hs
		895884 BIRC8_HUMAN (41-155): 2.84e-34: 129: 24.35		UB2D3_HUMAN (337-484): 1.86e-75: 235: 43.24
+	Hs
		851874 BIRC8_HUMAN (41-155): 2.84e-34: 129: 24.35		UB2E1_HUMAN (310-484): 6.38e-74: 233: 33.71
+	Hs
		828984 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		UBE2A_HUMAN (335-481): 2.56e-65: 209: 34.01
+	Hs
		896414 XIAP_HUMAN (2-156): 4.71e-38: 146: 21.25		UBE2N_HUMAN (340-487): 2.93e-63: 204: 37.16
+	Hs
		896521 BIRC8_HUMAN (41-155): 2.84e-34: 129: 24.35		UBE2N_HUMAN (340-487): 2.93e-63: 204: 37.16