HitPredict

Interactor 1: NOLC1 (Q14978)
Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130)
Gene: NOLC1

Interactor 2: REQU (Q92785)
Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem)
Gene: DPF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28533407
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 699 Hs			1 391
+	Mm
		964608 TOP2A_MOUSE (6-368): 7.3e-51: 194: 16.17		REQU_MOUSE (1-391): 7.14e-103: 311: 98.47
+	Hs
		973320 TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13		CHD3_HUMAN (43-382): 1.44e-49: 181: 13.23
+	Hs
		1018485 NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00		CHD3_HUMAN (43-382): 1.44e-49: 181: 13.23
+	Hs
		973332 TOP2B_HUMAN (6-463): 1.53e-66: 241: 14.13		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		1059617 NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		170369 NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00		TIF1A_HUMAN (25-391): 1.7e-32: 131: 14.06
+	Hs
		1061026 NOLC1_HUMAN (1-699): 6.47e-68: 237: 100.00		PHF10_HUMAN (226-384): 1.03e-31: 127: 35.19
+	Hs
		508970 TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44		CHD3_HUMAN (43-382): 1.44e-49: 181: 13.23
+	Hs
		508998 TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		509075 TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44		KAT6A_HUMAN (76-387): 3.75e-43: 162: 26.48
+	Hs
		170230 TOP2A_HUMAN (6-372): 1.49e-41: 165: 14.44		TIF1A_HUMAN (25-391): 1.7e-32: 131: 14.06
+	Dm
		332876 Q9VPR2_DROME (7-488): 6.96e-18: 90.1: 13.16		CHDM_DROME (45-384): 1.28e-48: 179: 16.35
+	Hs
		1018574 SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64		CHD3_HUMAN (43-382): 1.44e-49: 181: 13.23
+	Hs
		1059815 MINT_HUMAN (28-674): 3.38e-12: 72.4: 11.90		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		1059764 TITIN_HUMAN (8-622): 2.9e-11: 69.6: 12.44		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		1059726 SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		975294 TITIN_HUMAN (8-622): 2.9e-11: 69.6: 12.44		KMT2A_HUMAN (80-388): 8.66e-36: 141: 14.38
+	Hs
		152665 SRRM1_HUMAN (8-680): 2.28e-09: 62.7: 9.64		KMT2D_HUMAN (241-382): 8.36e-23: 102: 30.77