HitPredict

Interactor 1: TRF (Q27896)
TBP-related factor
Gene: TRF

Interactor 2: Q9VEL2 (Q9VEL2)
B-related factor 1
Gene: Brf

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	10850489, 25242320, 22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BRF1~TBP, TBP~TFIIB
Common GO terms	GO:0005634 - nucleus GO:0005667 - transcription regulator complex GO:0006352 - DNA-templated transcription initiation GO:0006383 - transcription by RNA polymerase III
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 224 Dm			1 662
+	Dm
		589972 TBP_DROME (22-223): 1.85e-98: 292: 55.39		Q9VEL2_DROME (1-662): 0: 644: 100.00
+	Hs
		589904 TBP_HUMAN (29-224): 7.7e-97: 287: 56.57		TF3B_HUMAN (3-662): 0: 599: 42.65
+	Sc
		526960 TBP_YEAST (6-223): 7.87e-99: 288: 48.89		TF3B_YEAST (4-532): 1.9e-140: 424: 28.88
+	Sp
		571843 TBP_SCHPO (16-223): 1.49e-95: 280: 53.37		TF3B_SCHPO (5-533): 3.49e-140: 420: 32.77
+	Dm
		661528 TRF_DROME (1-224): 1.57e-102: 297: 100.00		TF2B_DROME (2-291): 6.95e-119: 358: 21.36
+	Hs
		589827 TBP_HUMAN (29-224): 7.7e-97: 287: 56.57		TF2B_HUMAN (5-291): 3.38e-117: 354: 21.57
+	Mm
		661496 TBP_MOUSE (29-224): 5.81e-97: 286: 56.57		TF2B_MOUSE (5-291): 1.64e-117: 355: 21.57
+	Dm
		661530 Q8T052_DROME (1-223): 2.36e-82: 259: 32.74		TF2B_DROME (2-291): 6.95e-119: 358: 21.36
+	Sc
		526959 TBP_YEAST (6-223): 7.87e-99: 288: 48.89		TF2B_YEAST (1-279): 2.66e-90: 286: 18.53
+	Hs
		589923 TBP_HUMAN (29-224): 7.7e-97: 287: 56.57		BRF2_HUMAN (6-455): 1.21e-88: 284: 16.17
+	Hs
		913420 TBPL1_HUMAN (39-223): 6.54e-70: 213: 37.63		TF2B_HUMAN (5-291): 3.38e-117: 354: 21.57
+	At
		286708 TBP2_ARATH (20-223): 1.39e-95: 279: 50.98		PTF2_ARATH (5-309): 1.45e-66: 229: 15.84
+	Pf
		905369 TBP_PYRFU (46-131): 1.86e-22: 92.1: 36.05		TF2B_PYRFU (1-279): 2.08e-91: 287: 26.07