HitPredict

Interactor 1: INF2 (Q27J81)
Inverted formin-2 (HBEBP2-binding protein C)
Gene: INF2

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1249 Hs			1 618
+	Hs
		545409 INF2_HUMAN (1-1249): 0: 873: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		894070 INF2_HUMAN (1-1249): 0: 873: 100.00		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		1070213 INF2_HUMAN (1-1249): 0: 873: 100.00		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		951033 INF2_HUMAN (1-1249): 0: 873: 100.00		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		925315 INF2_HUMAN (1-1249): 0: 873: 100.00		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		914097 INF2_HUMAN (1-1249): 0: 873: 100.00		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		900525 INF2_HUMAN (1-1249): 0: 873: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		1100147 INF2_HUMAN (1-1249): 0: 873: 100.00		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		436333 INF2_HUMAN (1-1249): 0: 873: 100.00		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120464 INF2_HUMAN (1-1249): 0: 873: 100.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		545645 DIAP3_HUMAN (10-1092): 0: 666: 21.22		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		892621 DIAP3_HUMAN (10-1092): 0: 666: 21.22		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		894489 DIAP3_HUMAN (10-1092): 0: 666: 21.22		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		925658 DIAP3_HUMAN (10-1092): 0: 666: 21.22		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		914389 DIAP3_HUMAN (10-1092): 0: 666: 21.22		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		916010 DIAP3_HUMAN (10-1092): 0: 666: 21.22		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		900958 DIAP3_HUMAN (10-1092): 0: 666: 21.22		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		436532 DIAP3_HUMAN (10-1092): 0: 666: 21.22		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120664 DIAP3_HUMAN (10-1092): 0: 666: 21.22		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		564704 DIAP3_HUMAN (10-1092): 0: 666: 21.22		RHOQ_HUMAN (5-169): 2.02e-10: 62.8: 26.26