HitPredict

Interactor 1: MALT1 (Q2TBA3)
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog (EC 3.4.22.-) (Paracaspase)
Gene: MALT1

Interactor 2: BCL10 (Q9Z0H7)
B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CARD-containing molecule enhancing NF-kappa-B) (CARD-like apoptotic protein) (mCLAP) (CED-3/ICH-1 prodomain homologous E10-like regulator) (mCIPER) (Cellular homolog of vCARMEN) (cCARMEN) (Cellular-E10) (c-E10) (Mammalian CARD-containing adapter molecule E10) (mE10)
Gene: BCL10

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

The method score is based on:

Property	Details
Experiments	26936881, 16831874, 16495340, 19136564, 18227156
Identification Methods	affinity chromatography technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002020 - protease binding GO:0002096 - polkadots GO:0005829 - cytosol GO:0009620 - response to fungus GO:0019209 - kinase activator activity and 9 others more... GO:0031663 - lipopolysaccharide-mediated signaling pathway GO:0032449 - CBM complex GO:0043123 - positive regulation of canonical NF-kappaB signal transduction GO:0045087 - innate immune response GO:0048471 - perinuclear region of cytoplasm GO:0050852 - T cell receptor signaling pathway GO:0050856 - regulation of T cell receptor signaling pathway GO:0050870 - positive regulation of T cell activation GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	832
Mm

1	233

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024