Interactor 1: CDON (Q32MD9)
Cell adhesion molecule-related/down-regulated by oncogenes
Gene: CDON

Interactor 2: SHH (Q62226)
Sonic hedgehog protein (SHH) (EC 3.1.-.-) (HHG-1) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp) (Sonic hedgehog protein 19 kDa product)]
Gene: SHH

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 16647304, 17086203
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HH_signal~fn3
Common GO terms GO:0001708 - cell fate specification
GO:0002052 - positive regulation of neuroblast proliferation
GO:0005886 - plasma membrane
GO:0007224 - smoothened signaling pathway
GO:0007405 - neuroblast proliferation
and 11 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1250
Mm

1 437
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024