Protein: UB2V2
Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein)

Gene: UB2V2, UBE2V2
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q15819

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0000729 - DNA double-strand break processing
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

957744

UBE2N
Ubiquitin-conjugating enzyme E2 N

27

16

Small-scale

0.991

High

508033

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

6

20

Small-scale

0.941

High

1127720

HLTF
Helicase-like transcription factor

3

13

Small-scale

0.873

High

302536

RNF8
E3 ubiquitin-protein ligase RNF8

2

20

Small-scale

0.778

High

1154284

OTUB1
Ubiquitin thioesterase OTUB1

2

9

Small-scale

0.768

High

647561

UBA1
Ubiquitin-like modifier-activating enzyme 1

2

20

Small-scale

0.737

High

1135247

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

11

Small-scale

0.734

High

1093357

TRI32
E3 ubiquitin-protein ligase TRIM32

1

20

Small-scale

0.713

High

898235

R144A
E3 ubiquitin-protein ligase RNF144A

1

20

High-throughput

0.698

High

1022721

XIAP
E3 ubiquitin-protein ligase XIAP

1

20

High-throughput

0.698

High

1093621

MKRN3
E3 ubiquitin-protein ligase makorin-3

1

15

High-throughput

0.698

High

1154273

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

20

High-throughput

0.698

High

1154277

ZNRF1
E3 ubiquitin-protein ligase ZNRF1

1

20

High-throughput

0.698

High

1154288

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.698

High

1154294

TRIM5
Tripartite motif-containing protein 5

1

20

High-throughput

0.698

High

1103906

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

16

High-throughput

0.691

High

1107405

BIRC2
Baculoviral IAP repeat-containing protein 2

1

20

High-throughput

0.691

High

1154291

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

20

High-throughput

0.691

High

1090663

TRAF2
TNF receptor-associated factor 2

1

20

Small-scale

0.647

High

1154270

RN111
E3 ubiquitin-protein ligase Arkadia

1

20

Small-scale

0.647

High

1154272

UBE3B
Ubiquitin-protein ligase E3B

1

20

Small-scale

0.647

High

1154279

RFFL
E3 ubiquitin-protein ligase rififylin

1

20

Small-scale

0.647

High

1154281

TRI63
E3 ubiquitin-protein ligase TRIM63

1

20

Small-scale

0.647

High

1154282

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

20

Small-scale

0.647

High

1154292

TRI54
Tripartite motif-containing protein 54

1

20

Small-scale

0.647

High

1154304

CHIP
E3 ubiquitin-protein ligase CHIP

1

14

Small-scale

0.647

High

1154308

RNF11
RING finger protein 11

1

20

Small-scale

0.618

High

1154310

TRAF6
TNF receptor-associated factor 6

1

20

High-throughput

0.618

High

363336

EGFR
Epidermal growth factor receptor

2

0

Small-scale

0.582

High

783280

TRI23
E3 ubiquitin-protein ligase TRIM23

1

8

Small-scale

0.575

High

1154290

PCGF6
Polycomb group RING finger protein 6

1

20

High-throughput

0.575

High

1154302

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

1

5

Small-scale

0.550

High

413912

P53
Cellular tumor antigen p53

1

4

High-throughput

0.541

High

1154274

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

20

High-throughput

0.541

High

353876

BCL10
B-cell lymphoma/leukemia 10

1

0

Small-scale

0.537

High

336432

SVIL
Supervillin

1

2

High-throughput

0.536

High

994558

YBOX1
Y-box-binding protein 1

1

1

High-throughput

0.536

High

996709

TBA1B
Tubulin alpha-1B chain

1

1

High-throughput

0.536

High

1091673

MYO1E
Unconventional myosin-Ie

1

2

High-throughput

0.536

High

1154265

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

4

High-throughput

0.536

High

1154286

LRCH3
DISP complex protein LRCH3

1

1

High-throughput

0.536

High

1154299

RAI14
Ankycorbin

1

8

High-throughput

0.536

High

1154301

POLK
DNA polymerase kappa

1

2

High-throughput

0.536

High

1154303

MYO5B
Unconventional myosin-Vb

1

1

High-throughput

0.536

High

1154305

MINP1
Multiple inositol polyphosphate phosphatase 1

1

1

High-throughput

0.536

High

1154306

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.518

High

142343

PEX7
Peroxisomal targeting signal 2 receptor

1

5

High-throughput

0.514

High

962085

RHOA
Transforming protein RhoA

1

0

High-throughput

0.513

High

1150535

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.513

High

1154264

TIGD6
Tigger transposable element-derived protein 6

1

0

High-throughput

0.513

High

1154276

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.513

High

1154298

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.513

High

1154311

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

High-throughput

0.513

High

211567

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

20

Small-scale

0.501

High

1154267

RC3H1
Roquin-1

1

10

Small-scale

0.501

High

1154296

RC3H2
Roquin-2

1

11

Small-scale

0.501

High

1122009

EFR3A
Protein EFR3 homolog A

1

2

High-throughput

0.489

High

1154269

MPRIP
Myosin phosphatase Rho-interacting protein

1

3

High-throughput

0.489

High

567409

TCTP
Translationally-controlled tumor protein

1

5

High-throughput

0.479

High

698693

CALX
Calnexin

1

2

High-throughput

0.479

High

1154271

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1154280

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

Small-scale

0.479

High

1154266

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

885580

PRI2
DNA primase large subunit

1

0

High-throughput

0.458

High

1154278

TRUB1
Pseudouridylate synthase TRUB1

1

0

High-throughput

0.458

High

1154289

OVOL2
Transcription factor Ovo-like 2

1

0

Small-scale

0.458

High

929956

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

High-throughput

0.457

High

1104789

SNTA1
Alpha-1-syntrophin

1

5

High-throughput

0.457

High

1154268

RIF1
Telomere-associated protein RIF1

1

4

High-throughput

0.457

High

1154295

SUV92
Histone-lysine N-methyltransferase SUV39H2

1

3

High-throughput

0.457

High

1154287

LMTK3
Serine/threonine-protein kinase LMTK3

1

3

High-throughput

0.457

High

529867

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High

628620

CAP7
Azurocidin

1

2

High-throughput

0.445

High

1010755

SSBP2
Single-stranded DNA-binding protein 2

1

1

High-throughput

0.445

High

1154275

DND1
Dead end protein homolog 1

1

2

High-throughput

0.445

High

254616

EIF1B
Eukaryotic translation initiation factor 1b

1

1

High-throughput

0.437

High

1154297

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.426

High

1154300

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.426

High

1154307

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.426

High

1154309

MSRB2
Methionine-R-sulfoxide reductase B2, mitochondrial

1

0

High-throughput

0.426

High

1154285

IGS21
Immunoglobulin superfamily member 21

1

0

High-throughput

0.282

High

1154283

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.238

Low

1154293

NMNA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025