Interactor 1: LRRK1 (Q38SD2)
Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1)
Gene: LRRK1

Interactor 2: PAK6 (Q9NQU5)
Serine/threonine-protein kinase PAK 6 (EC 2.7.11.1) (PAK-5) (p21-activated kinase 6) (PAK-6)
Gene: PAK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 29513927, 24947832
Identification Methods pull down, protein array
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PBD~Pkinase, Pkinase~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0016310 - phosphorylation
GO:0035556 - intracellular signal transduction
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 2015
Hs

1 681
+ Hs
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024