Protein: ERLEC
Endoplasmic reticulum lectin 1 (ER lectin) (Erlectin) (XTP3-transactivated gene B protein)

Gene: ERLEC, ERLEC1
Organism: Homo sapiens
Interactions: 148
UniProt ID: Q96DZ1

Gene Ontology (top 5):
GO:0005788 - endoplasmic reticulum lumen
GO:0030968 - endoplasmic reticulum unfolded protein response
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0036503 - ERAD pathway
GO:0044322 - endoplasmic reticulum quality control compartment

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1388116

SE1L1
Protein sel-1 homolog 1

4

4

Small-scale

0.683

High

617334

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

3

5

High-throughput

0.667

High

1388085

ATF6B
Cyclic AMP-dependent transcription factor ATF-6 beta

3

5

High-throughput

0.667

High

1287404

SYVN1
E3 ubiquitin-protein ligase synoviolin

3

5

Small-scale

0.656

High

369380

A1AT
Alpha-1-antitrypsin

3

5

Small-scale

0.640

High

1310014

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

2

1

High-throughput

0.628

High

1105539

OS9
Protein OS-9

2

1

Small-scale

0.611

High

1388089

CNTP3
Contactin-associated protein-like 3

3

2

High-throughput

0.609

High

455998

ASGR2
Asialoglycoprotein receptor 2

2

5

Small-scale

0.584

High

535399

BIP
Endoplasmic reticulum chaperone BiP

2

2

Small-scale

0.584

High

1388101

FBX6
F-box only protein 6

2

1

High-throughput

0.584

High

1388109

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

2

4

High-throughput

0.558

High

1207887

S27A3
Long-chain fatty acid transport protein 3

2

1

High-throughput

0.549

High

1388093

UN93B
Protein unc-93 homolog B1

2

1

High-throughput

0.549

High

1388094

CHST8
Carbohydrate sulfotransferase 8

2

1

High-throughput

0.549

High

230391

CREB3
Cyclic AMP-responsive element-binding protein 3

1

5

High-throughput

0.536

High

1388091

DERL2
Derlin-2

1

3

High-throughput

0.536

High

1388115

FA8A1
Protein FAM8A1

1

1

High-throughput

0.536

High

1388128

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

2

High-throughput

0.536

High

1163797

PTPRO
Receptor-type tyrosine-protein phosphatase O

2

1

High-throughput

0.533

High

952458

UB2G2
Ubiquitin-conjugating enzyme E2 G2

1

0

High-throughput

0.513

High

1388132

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

0

High-throughput

0.513

High

251108

B4GT3
Beta-1,4-galactosyltransferase 3

1

1

High-throughput

0.489

High

280768

PR40A
Pre-mRNA-processing factor 40 homolog A

1

2

High-throughput

0.489

High

318377

MYO1D
Unconventional myosin-Id

1

3

High-throughput

0.489

High

463190

YES
Tyrosine-protein kinase Yes

1

1

High-throughput

0.489

High

604406

ASM
Sphingomyelin phosphodiesterase

1

1

High-throughput

0.489

High

875751

PRC2A
Protein PRRC2A

1

3

High-throughput

0.489

High

896284

PEX5
Peroxisomal targeting signal 1 receptor

1

1

High-throughput

0.489

High

1034796

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

1

High-throughput

0.489

High

1142139

P2RY6
P2Y purinoceptor 6

1

1

High-throughput

0.489

High

1148458

SAFB1
Scaffold attachment factor B1

1

1

High-throughput

0.489

High

1194699

GXLT1
Glucoside xylosyltransferase 1

1

2

High-throughput

0.489

High

1229845

CYTSA
Cytospin-A

1

1

High-throughput

0.489

High

1231132

SCAR3
Scavenger receptor class A member 3

1

2

High-throughput

0.489

High

1250753

MPRIP
Myosin phosphatase Rho-interacting protein

1

2

High-throughput

0.489

High

1279884

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

1

High-throughput

0.489

High

1359433

LMO7
LIM domain only protein 7

1

1

High-throughput

0.489

High

1363122

CLC2B
C-type lectin domain family 2 member B

1

5

High-throughput

0.489

High

1388083

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

1

High-throughput

0.489

High

1388086

DIDO1
Death-inducer obliterator 1

1

1

High-throughput

0.489

High

1388095

TARA
TRIO and F-actin-binding protein

1

2

High-throughput

0.489

High

1388096

CPVL
Probable serine carboxypeptidase CPVL

1

1

High-throughput

0.489

High

1388099

SPRNG
SREBP regulating gene protein

1

1

High-throughput

0.489

High

1388100

MYO5C
Unconventional myosin-Vc

1

2

High-throughput

0.489

High

1388105

SLTM
SAFB-like transcription modulator

1

2

High-throughput

0.489

High

1388114

CING
Cingulin

1

1

High-throughput

0.489

High

1388119

CLC2D
C-type lectin domain family 2 member D

1

5

High-throughput

0.489

High

1388121

MYO5B
Unconventional myosin-Vb

1

2

High-throughput

0.489

High

1388123

AT1B4
Protein ATP1B4

1

1

High-throughput

0.489

High

1388126

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

4

High-throughput

0.489

High

1388127

KLK5
Kallikrein-5

1

3

High-throughput

0.489

High

1388129

PRC2C
Protein PRRC2C

1

2

High-throughput

0.489

High

573617

ENPL
Endoplasmin

1

1

Small-scale

0.479

High

1365484

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

4

High-throughput

0.479

High

1388090

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

4

Small-scale

0.479

High

188957

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.470

High

1286862

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.470

High

218613

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

242551

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

1312575

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

465613

IGF1R
Insulin-like growth factor 1 receptor

1

3

High-throughput

0.457

High

178363

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.437

High

284407

CLN5
Bis(monoacylglycero)phosphate synthase CLN5

1

1

High-throughput

0.437

High

335398

GDF11
Growth/differentiation factor 11

1

3

High-throughput

0.437

High

622660

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

1

High-throughput

0.437

High

774550

BASI
Basigin

1

2

High-throughput

0.437

High

1179124

TECT1
Tectonic-1

1

1

High-throughput

0.437

High

1255009

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1308186

PLD3
5'-3' exonuclease PLD3

1

3

High-throughput

0.437

High

1313792

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

1324160

PLD6
Mitochondrial cardiolipin hydrolase

1

1

High-throughput

0.437

High

1334503

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.437

High

1385225

PLD4
5'-3' exonuclease PLD4

1

3

High-throughput

0.437

High

1388102

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.437

High

1388103

EMIL3
EMILIN-3

1

7

High-throughput

0.437

High

1388104

T106B
Transmembrane protein 106B

1

1

High-throughput

0.437

High

1388117

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

1388122

CLC4E
C-type lectin domain family 4 member E

1

3

High-throughput

0.437

High

104206

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

184022

S22A1
Solute carrier family 22 member 1

1

7

High-throughput

0.407

High

303268

S22A5
Organic cation/carnitine transporter 2

1

5

High-throughput

0.407

High

350729

NOE2
Noelin-2

1

2

High-throughput

0.407

High

424305

INHA
Inhibin alpha chain

1

3

High-throughput

0.407

High

519651

LYAG
Lysosomal alpha-glucosidase

1

1

High-throughput

0.407

High

869645

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

1

High-throughput

0.407

High

1060383

SLC31
Amino acid transporter heavy chain SLC3A1

1

1

High-throughput

0.407

High

1131591

MFS10
Major facilitator superfamily domain-containing protein 10

1

5

High-throughput

0.407

High

1224947

S22AA
Solute carrier family 22 member 10

1

7

High-throughput

0.407

High

1230837

SL9A4
Sodium/hydrogen exchanger 4

1

2

High-throughput

0.407

High

1236266

MFSD5
Molybdate-anion transporter

1

1

High-throughput

0.407

High

1242198

NPAL3
NIPA-like protein 3

1

1

High-throughput

0.407

High

1251785

S39A5
Zinc transporter ZIP5

1

2

High-throughput

0.407

High

1259244

NCKX5
Sodium/potassium/calcium exchanger 5

1

1

High-throughput

0.407

High

1356671

S22AH
Solute carrier family 22 member 17

1

7

High-throughput

0.407

High

1388082

B3A4
Anion exchange protein 4

1

3

High-throughput

0.407

High

1388088

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

3

High-throughput

0.407

High

1388125

S22AE
Solute carrier family 22 member 14

1

7

High-throughput

0.407

High

1177241

MICA
MHC class I polypeptide-related sequence A

3

0

High-throughput

0.347

High

1154418

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.282

High

171303

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

0

High-throughput

0.279

Low

253878

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

298048

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.279

Low

317252

AL1A2
Retinal dehydrogenase 2

1

0

High-throughput

0.279

Low

336469

SVIL
Supervillin

1

0

High-throughput

0.279

Low

377116

GLHA
Glycoprotein hormones alpha chain

1

0

High-throughput

0.279

Low

635432

C4BPB
C4b-binding protein beta chain

1

0

High-throughput

0.279

Low

692776

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.279

Low

702029

TMOD1
Tropomodulin-1

1

0

High-throughput

0.279

Low

898516

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.279

Low

909129

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.279

Low

1058909

ZO1
Tight junction protein 1

1

0

High-throughput

0.279

Low

1084021

SIA4A
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

1

0

High-throughput

0.279

Low

1088281

SFSWA
Splicing factor, suppressor of white-apricot homolog

1

0

High-throughput

0.279

Low

1270763

DDX46
Probable ATP-dependent RNA helicase DDX46

1

0

High-throughput

0.279

Low

1294411

SPAS2
Spermatogenesis-associated serine-rich protein 2

1

0

High-throughput

0.279

Low

1309140

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.279

Low

1388079

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.279

Low

1388080

LRCH3
DISP complex protein LRCH3

1

0

High-throughput

0.279

Low

1388081

DOCK7
Dedicator of cytokinesis protein 7

1

0

High-throughput

0.279

Low

1388084

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.279

Low

1388087

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.279

Low

1388092

NYX
Nyctalopin

1

0

High-throughput

0.279

Low

1388097

SEM4A
Semaphorin-4A

1

0

High-throughput

0.279

Low

1388098

CST9L
Cystatin-9-like

1

0

High-throughput

0.279

Low

1388106

CUED1
CUE domain-containing protein 1

1

0

High-throughput

0.279

Low

1388107

FBX34
F-box only protein 34

1

0

High-throughput

0.279

Low

1388110

CDK12
Cyclin-dependent kinase 12

1

0

High-throughput

0.279

Low

1388111

ARHGC
Rho guanine nucleotide exchange factor 12

1

0

High-throughput

0.279

Low

1388112

RAI14
Ankycorbin

1

0

High-throughput

0.279

Low

1388118

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.279

Low

1388124

ZC3H4
Zinc finger CCCH domain-containing protein 4

1

0

High-throughput

0.279

Low

1388131

LIPG
Endothelial lipase

1

0

High-throughput

0.279

Low

106440

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

377225

SOMA
Somatotropin

1

0

High-throughput

0.249

Low

1220723

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.249

Low

1249100

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1388113

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.249

Low

1388120

FBXL4
F-box/LRR-repeat protein 4

1

0

Small-scale

0.249

Low

1388130

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

2113

TVA20
T cell receptor alpha variable 20

1

0

High-throughput

0.232

Low

132921

S28A1
Sodium/nucleoside cotransporter 1

1

0

High-throughput

0.232

Low

653495

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low

1227234

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

1254170

MOT12
Monocarboxylate transporter 12

1

0

High-throughput

0.232

Low

1346753

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

0

High-throughput

0.232

Low

1359758

S13A3
Na(+)/dicarboxylate cotransporter 3

1

0

High-throughput

0.232

Low

1388108

SC5A4
Probable glucose sensor protein SLC5A4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025