Interactor 1: ROCK1 (Q13464)
Rho-associated protein kinase 1 (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-35) (Rho-associated, coiled-coil-containing protein kinase 1) (Rho-associated, coiled-coil-containing protein kinase I) (ROCK-I) (p160 ROCK-1) (p160ROCK)
Gene: ROCK1

Interactor 2: RTKN2 (Q8IZC4)
Rhotekin-2 (Pleckstrin homology domain-containing family K member 1) (PH domain-containing family K member 1)
Gene: RTKN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 40437099
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Pkinase
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1354
Hs

1 609
+ Hs
+ Hs
+ Dm

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Last updated: 11Aug2025