HitPredict

Interactor 1: MPK6 (Q39026)
Mitogen-activated protein kinase 6 (AtMPK6) (MAP kinase 6) (EC 2.7.11.24)
Gene: MPK6

Interactor 2: DUS1B (Q9M8K7)
Dual specificity protein phosphatase 1B (AtDsPTP1B) (EC 3.1.3.16) (EC 3.1.3.48) (MAPK phosphatase 2) (AtMKP2)
Gene: DSPTP1B

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	20626661
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	DSPc~Pkinase
Common GO terms	GO:0005634 - nucleus GO:0006979 - response to oxidative stress
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 395 At			1 167
+	At
		1106575 MPK6_ARATH (1-395): 6.49e-168: 476: 100.00		MKP1_ARATH (11-165): 1.72e-53: 182: 31.41
+	At
		1106250 MPK3_ARATH (37-391): 1.37e-151: 434: 76.12		DUS1B_ARATH (1-167): 5.21e-74: 220: 100.00
+	Hs
		659288 MK14_HUMAN (46-392): 1.62e-148: 426: 46.71		DUS1_HUMAN (19-166): 2.85e-66: 207: 35.81
+	Hs
		1024807 MK14_HUMAN (46-392): 1.62e-148: 426: 46.71		DUS4_HUMAN (19-167): 1.58e-65: 206: 35.57
+	At
		1106284 MPK3_ARATH (37-391): 1.37e-151: 434: 76.12		DUS1_ARATH (20-164): 2.88e-62: 192: 61.38
+	Hs
		985178 MK14_HUMAN (46-392): 1.62e-148: 426: 46.71		DUS2_HUMAN (19-164): 4.18e-64: 200: 36.30
+	Mm
		814046 MK14_MOUSE (46-392): 8.97e-149: 427: 46.71		DUS2_MOUSE (19-164): 7.61e-63: 197: 35.62
+	Hs
		1082629 MK14_HUMAN (46-392): 1.62e-148: 426: 46.71		DUS16_HUMAN (24-167): 6.04e-59: 195: 30.35
+	Hs
		1082621 MK14_HUMAN (46-392): 1.62e-148: 426: 46.71		DUS9_HUMAN (25-164): 1.61e-60: 193: 36.62
+	Hs
		1082561 MK14_HUMAN (46-392): 1.62e-148: 426: 46.71		DUS7_HUMAN (25-167): 8.33e-60: 192: 34.48
+	Hs
		1082560 MK14_HUMAN (46-392): 1.62e-148: 426: 46.71		DUS6_HUMAN (25-167): 1.57e-58: 188: 35.17
+	Hs
		658798 MK01_HUMAN (62-394): 8.58e-140: 404: 51.78		DUS1_HUMAN (19-166): 2.85e-66: 207: 35.81
+	Hs
		658919 MK01_HUMAN (62-394): 8.58e-140: 404: 51.78		DUS4_HUMAN (19-167): 1.58e-65: 206: 35.57
+	Hs
		658903 MK01_HUMAN (62-394): 8.58e-140: 404: 51.78		DUS2_HUMAN (19-164): 4.18e-64: 200: 36.30
+	Hs
		658960 MK01_HUMAN (62-394): 8.58e-140: 404: 51.78		DUS5_HUMAN (19-167): 6.94e-63: 199: 35.57
+	Mm
		926403 MK01_MOUSE (62-394): 8.37e-140: 404: 51.78		DUS2_MOUSE (19-164): 7.61e-63: 197: 35.62
+	Hs
		1082628 MK14_HUMAN (46-392): 1.62e-148: 426: 46.71		DUS26_HUMAN (16-164): 6.79e-54: 171: 32.08
+	Mm
		926439 MK01_MOUSE (62-394): 8.37e-140: 404: 51.78		DUS6_MOUSE (25-167): 1.57e-58: 188: 35.17
+	Rn
		926496 MK01_RAT (62-394): 8.37e-140: 404: 51.78		DUS6_RAT (25-167): 1.57e-58: 188: 35.17
+	Hs
		658923 MK01_HUMAN (62-394): 8.58e-140: 404: 51.78		DUS8_HUMAN (24-163): 2.05e-54: 183: 33.33