Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
SMAD4
Mothers against decapentaplegic homolog 4 |
17 |
19 |
Small-scale |
0.986 | High |
|
|
SMAD6
Mothers against decapentaplegic homolog 6 |
4 |
19 |
Small-scale |
0.900 | High |
|
|
SMAD1
Mothers against decapentaplegic homolog 1 |
3 |
19 |
Small-scale |
0.868 | High |
|
|
SKI
Ski oncogene |
3 |
16 |
Small-scale |
0.857 | High |
|
|
SMAD2
Mothers against decapentaplegic homolog 2 |
3 |
19 |
Small-scale |
0.849 | High |
|
|
SMAD3
Mothers against decapentaplegic homolog 3 |
2 |
19 |
Small-scale |
0.783 | High |
|
|
SMUF1
E3 ubiquitin-protein ligase SMURF1 |
17 |
20 |
Small-scale |
0.767 | High |
|
|
SMUF2
E3 ubiquitin-protein ligase SMURF2 |
11 |
20 |
Small-scale |
0.759 | High |
|
|
PSB4
Proteasome subunit beta type-4 |
6 |
1 |
Small-scale |
0.733 | High |
|
|
MAN1
Inner nuclear membrane protein Man1 |
5 |
14 |
Small-scale |
0.717 | High |
|
|
EP300
Histone acetyltransferase p300 |
5 |
20 |
Small-scale |
0.702 | High |
|
|
CHIP
E3 ubiquitin-protein ligase CHIP |
3 |
5 |
Small-scale |
0.692 | High |
|
|
YAP1
Transcriptional coactivator YAP1 |
2 |
20 |
Small-scale |
0.660 | High |
|
|
SMAD5
Mothers against decapentaplegic homolog 5 |
1 |
20 |
High-throughput |
0.656 | High |
|
|
MK01
Mitogen-activated protein kinase 1 |
3 |
3 |
Small-scale |
0.655 | High |
|
|
CBP
CREB-binding protein |
3 |
17 |
Small-scale |
0.646 | High |
|
|
ACVR1
Activin receptor type-1 |
3 |
20 |
Small-scale |
0.642 | High |
|
|
RUNX2
Runt-related transcription factor 2 |
3 |
16 |
Small-scale |
0.640 | High |
|
|
ANDR
Androgen receptor |
2 |
14 |
Small-scale |
0.639 | High |
|
|
PIAS4
E3 SUMO-protein ligase PIAS4 |
2 |
16 |
Small-scale |
0.627 | High |
|
|
BMR1A
Bone morphogenetic protein receptor type-1A |
2 |
20 |
Small-scale |
0.619 | High |
|
|
SMAD7
Mothers against decapentaplegic homolog 7 |
1 |
18 |
Small-scale |
0.618 | High |
|
|
SKIL
Ski-like protein |
1 |
16 |
Small-scale |
0.618 | High |
|
|
EPN2
Epsin-2 |
2 |
3 |
High-throughput |
0.606 | High |
|
|
ACVL1
Activin receptor type-1-like |
2 |
20 |
Small-scale |
0.602 | High |
|
|
MED6
Mediator of RNA polymerase II transcription subunit 6 |
2 |
2 |
Small-scale |
0.601 | High |
|
|
ZEB2
Zinc finger E-box-binding homeobox 2 |
2 |
15 |
Small-scale |
0.600 | High |
|
|
NEDD4
E3 ubiquitin-protein ligase NEDD4 |
2 |
20 |
Small-scale |
0.600 | High |
|
|
CASL
Enhancer of filamentation 1 |
2 |
5 |
Small-scale |
0.600 | High |
|
|
ZCH12
Zinc finger CCHC domain-containing protein 12 |
2 |
0 |
Small-scale |
0.598 | High |
|
|
MEN1
Menin |
2 |
5 |
Small-scale |
0.584 | High |
|
|
ZN423
Zinc finger protein 423 |
2 |
5 |
Small-scale |
0.584 | High |
|
|
USP9X
Ubiquitin carboxyl-terminal hydrolase 9X |
2 |
7 |
Small-scale |
0.584 | High |
|
|
WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1 |
2 |
20 |
Small-scale |
0.584 | High |
|
|
UBP15
Ubiquitin carboxyl-terminal hydrolase 15 |
2 |
12 |
Small-scale |
0.584 | High |
|
|
CDK8
Cyclin-dependent kinase 8 |
1 |
10 |
Small-scale |
0.578 | High |
|
|
HXC8
Homeobox protein Hox-C8 |
1 |
12 |
Small-scale |
0.573 | High |
|
|
IPO8
Importin-8 |
1 |
6 |
Small-scale |
0.561 | High |
|
|
NKX32
Homeobox protein Nkx-3.2 |
1 |
15 |
Small-scale |
0.561 | High |
|
|
TAPT1
Transmembrane anterior posterior transformation protein 1 homolog |
1 |
1 |
Small-scale |
0.561 | High |
|
|
HIPK2
Homeodomain-interacting protein kinase 2 |
1 |
18 |
Small-scale |
0.561 | High |
|
|
DDX5
Probable ATP-dependent RNA helicase DDX5 |
1 |
10 |
Small-scale |
0.554 | High |
|
|
RNC
Ribonuclease 3 |
1 |
3 |
Small-scale |
0.554 | High |
|
|
MEP50
Methylosome protein WDR77 |
1 |
3 |
Small-scale |
0.552 | High |
|
|
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1 |
1 |
2 |
High-throughput |
0.541 | High |
|
|
TLR2
Toll-like receptor 2 |
1 |
1 |
High-throughput |
0.541 | High |
|
|
CREST
Calcium-responsive transactivator |
1 |
6 |
High-throughput |
0.541 | High |
|
|
RASN
GTPase NRas |
1 |
2 |
High-throughput |
0.541 | High |
|
|
ERBB2
Receptor tyrosine-protein kinase erbB-2 |
1 |
5 |
High-throughput |
0.541 | High |
|
|
HXA5
Homeobox protein Hox-A5 |
1 |
9 |
High-throughput |
0.541 | High |
|
|
CCND1
G1/S-specific cyclin-D1 |
1 |
1 |
High-throughput |
0.541 | High |
|
|
APC
Adenomatous polyposis coli protein |
1 |
3 |
High-throughput |
0.541 | High |
|
|
MLH1
DNA mismatch repair protein Mlh1 |
1 |
1 |
High-throughput |
0.541 | High |
|
|
PTN12
Tyrosine-protein phosphatase non-receptor type 12 |
1 |
2 |
High-throughput |
0.541 | High |
|
|
NF2L2
Nuclear factor erythroid 2-related factor 2 |
1 |
15 |
Small-scale |
0.541 | High |
|
|
FBXW7
F-box/WD repeat-containing protein 7 |
1 |
5 |
High-throughput |
0.541 | High |
|
|
RHG07
Rho GTPase-activating protein 7 |
1 |
3 |
High-throughput |
0.541 | High |
|
|
MLH3
DNA mismatch repair protein Mlh3 |
1 |
1 |
High-throughput |
0.541 | High |
|
|
AXIN2
Axin-2 |
1 |
7 |
High-throughput |
0.541 | High |
|
|
EGLN
Endoglin |
1 |
1 |
High-throughput |
0.536 | High |
|
|
IDD
Integral membrane protein DGCR2/IDD |
1 |
4 |
High-throughput |
0.536 | High |
|
|
KDM3B
Lysine-specific demethylase 3B |
1 |
5 |
High-throughput |
0.536 | High |
|
|
TM192
Transmembrane protein 192 |
1 |
2 |
High-throughput |
0.536 | High |
|
|
TET2
Methylcytosine dioxygenase TET2 |
1 |
0 |
High-throughput |
0.529 | High |
|
|
CTNA1
Catenin alpha-1 |
1 |
0 |
High-throughput |
0.518 | High |
|
|
MSH2
DNA mismatch repair protein Msh2 |
1 |
0 |
High-throughput |
0.518 | High |
|
|
MUTYH
Adenine DNA glycosylase |
1 |
0 |
High-throughput |
0.518 | High |
|
|
MED24
Mediator of RNA polymerase II transcription subunit 24 |
1 |
5 |
Small-scale |
0.515 | High |
|
|
UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3 |
1 |
7 |
Small-scale |
0.515 | High |
|
|
MED15
Mediator of RNA polymerase II transcription subunit 15 |
1 |
20 |
Small-scale |
0.515 | High |
|
|
OPTN
Optineurin |
1 |
3 |
High-throughput |
0.515 | High |
|
|
PSD11
26S proteasome non-ATPase regulatory subunit 11 |
1 |
4 |
High-throughput |
0.508 | High |
|
|
KMT2D
Histone-lysine N-methyltransferase 2D |
1 |
14 |
High-throughput |
0.508 | High |
|
|
MAST4
Microtubule-associated serine/threonine-protein kinase 4 |
1 |
20 |
High-throughput |
0.508 | High |
|
|
HBP1
HMG box-containing protein 1 |
1 |
20 |
High-throughput |
0.508 | High |
|
|
SF3B1
Splicing factor 3B subunit 1 |
1 |
5 |
High-throughput |
0.508 | High |
|
|
PIAS1
E3 SUMO-protein ligase PIAS1 |
1 |
16 |
High-throughput |
0.508 | High |
|
|
AP2A2
AP-2 complex subunit alpha-2 |
1 |
2 |
High-throughput |
0.508 | High |
|
|
RU17
U1 small nuclear ribonucleoprotein 70 kDa |
1 |
8 |
High-throughput |
0.508 | High |
|
|
RFX1
MHC class II regulatory factor RFX1 |
1 |
7 |
High-throughput |
0.508 | High |
|
|
SOX5
Transcription factor SOX-5 |
1 |
20 |
High-throughput |
0.508 | High |
|
|
ZNF76
Zinc finger protein 76 |
1 |
3 |
High-throughput |
0.508 | High |
|
|
NOTC2
Neurogenic locus notch homolog protein 2 |
1 |
12 |
High-throughput |
0.508 | High |
|
|
TTF1
Transcription termination factor 1 |
1 |
1 |
High-throughput |
0.508 | High |
|
|
CAMP1
Calmodulin-regulated spectrin-associated protein 1 |
1 |
1 |
High-throughput |
0.508 | High |
|
|
MGAP
MAX gene-associated protein |
1 |
6 |
High-throughput |
0.508 | High |
|
|
ZSCA4
Zinc finger and SCAN domain-containing protein 4 |
1 |
4 |
High-throughput |
0.508 | High |
|
|
SFRP3
Secreted frizzled-related protein 3 |
1 |
2 |
High-throughput |
0.508 | High |
|
|
SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 |
1 |
2 |
High-throughput |
0.508 | High |
|
|
Z512B
Zinc finger protein 512B |
1 |
2 |
High-throughput |
0.508 | High |
|
|
ANR27
Ankyrin repeat domain-containing protein 27 |
1 |
4 |
High-throughput |
0.508 | High |
|
|
INP4A
Inositol polyphosphate-4-phosphatase type I A |
1 |
1 |
High-throughput |
0.508 | High |
|
|
ZN251
Zinc finger protein 251 |
1 |
1 |
High-throughput |
0.508 | High |
|
|
ZDHC3
Palmitoyltransferase ZDHHC3 |
1 |
1 |
High-throughput |
0.508 | High |
|
|
MRTFB
Myocardin-related transcription factor B |
1 |
7 |
High-throughput |
0.508 | High |
|
|
TTF2
Transcription termination factor 2 |
1 |
5 |
High-throughput |
0.508 | High |
|
|
CILK1
Serine/threonine-protein kinase ICK |
1 |
3 |
High-throughput |
0.508 | High |
|
|
ZN510
Zinc finger protein 510 |
1 |
3 |
High-throughput |
0.508 | High |
|
|
CHMP3
Charged multivesicular body protein 3 |
1 |
3 |
High-throughput |
0.508 | High |
|
|
STA13
StAR-related lipid transfer protein 13 |
1 |
4 |
High-throughput |
0.508 | High |
|
|
GMEB1
Glucocorticoid modulatory element-binding protein 1 |
1 |
1 |
High-throughput |
0.508 | High |
|
|
DVL1
Segment polarity protein dishevelled homolog DVL-1 |
1 |
16 |
Small-scale |
0.501 | High |
|
|
A4
Amyloid-beta precursor protein |
1 |
3 |
High-throughput |
0.501 | High |
|
|
TYY1
Transcriptional repressor protein YY1 |
1 |
11 |
Small-scale |
0.501 | High |
|
|
MP2K3
Dual specificity mitogen-activated protein kinase kinase 3 |
1 |
17 |
High-throughput |
0.501 | High |
|
|
GSK3B
Glycogen synthase kinase-3 beta |
1 |
8 |
Small-scale |
0.501 | High |
|
|
CDK7
Cyclin-dependent kinase 7 |
1 |
2 |
Small-scale |
0.501 | High |
|
|
CDK9
Cyclin-dependent kinase 9 |
1 |
7 |
Small-scale |
0.501 | High |
|
|
FOXG1
Forkhead box protein G1 |
1 |
7 |
Small-scale |
0.501 | High |
|
|
MECOM
Histone-lysine N-methyltransferase MECOM |
1 |
15 |
Small-scale |
0.501 | High |
|
|
STK11
Serine/threonine-protein kinase STK11 |
1 |
1 |
High-throughput |
0.501 | High |
|
|
PARD3
Partitioning defective 3 homolog |
1 |
7 |
Small-scale |
0.501 | High |
|
|
NGN1
Neurogenin-1 |
1 |
3 |
Small-scale |
0.501 | High |
|
|
ERBIN
Erbin |
1 |
10 |
Small-scale |
0.501 | High |
|
|
DACH1
Dachshund homolog 1 |
1 |
2 |
High-throughput |
0.501 | High |
|
|
DNM3L
DNA |
1 |
2 |
Small-scale |
0.501 | High |
|
|
PGFRL
Platelet-derived growth factor receptor-like protein |
1 |
1 |
High-throughput |
0.494 | High |
|
|
ALDR
Aldo-keto reductase family 1 member B1 |
1 |
0 |
High-throughput |
0.486 | High |
|
|
XPC
DNA repair protein complementing XP-C cells |
1 |
0 |
High-throughput |
0.486 | High |
|
|
PUM1
Pumilio homolog 1 |
1 |
0 |
High-throughput |
0.486 | High |
|
|
I2BP1
Interferon regulatory factor 2-binding protein 1 |
1 |
0 |
High-throughput |
0.486 | High |
|
|
PSMD1
26S proteasome non-ATPase regulatory subunit 1 |
1 |
0 |
High-throughput |
0.486 | High |
|
|
LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C |
1 |
1 |
High-throughput |
0.481 | High |
|
|
UBC
Polyubiquitin-C [Cleaved into: Ubiquitin] |
1 |
6 |
Small-scale |
0.481 | High |
|
|
OAZ1
Ornithine decarboxylase antizyme 1 |
1 |
1 |
Small-scale |
0.481 | High |
|
|
SNIP1
Smad nuclear-interacting protein 1 |
1 |
2 |
Small-scale |
0.481 | High |
|
|
TCF20
Transcription factor 20 |
1 |
4 |
High-throughput |
0.481 | High |
|
|
OAZ3
Ornithine decarboxylase antizyme 3 |
1 |
1 |
Small-scale |
0.481 | High |
|
|
MED19
Mediator of RNA polymerase II transcription subunit 19 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
IPO5
Importin-5 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate |
1 |
9 |
Small-scale |
0.479 | High |
|
|
XPO1
Exportin-1 |
1 |
10 |
High-throughput |
0.479 | High |
|
|
KDM6B
Lysine-specific demethylase 6B |
1 |
6 |
Small-scale |
0.479 | High |
|
|
CTDSL
CTD small phosphatase-like protein |
1 |
6 |
Small-scale |
0.479 | High |
|
|
FOXO3
Forkhead box protein O3 |
1 |
19 |
Small-scale |
0.479 | High |
|
|
MED14
Mediator of RNA polymerase II transcription subunit 14 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
IPO7
Importin-7 |
1 |
7 |
Small-scale |
0.479 | High |
|
|
ACL6A
Actin-like protein 6A |
1 |
2 |
Small-scale |
0.479 | High |
|
|
P53
Cellular tumor antigen p53 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
EGR1
Early growth response protein 1 |
1 |
6 |
High-throughput |
0.479 | High |
|
|
TAF1
Transcription initiation factor TFIID subunit 1 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
PAX6
Paired box protein Pax-6 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
NU214
Nuclear pore complex protein Nup214 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
PPM1A
Protein phosphatase 1A |
1 |
2 |
Small-scale |
0.479 | High |
|
|
ZEB1
Zinc finger E-box-binding homeobox 1 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
STAT3
Signal transducer and activator of transcription 3 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
TAF6
Transcription initiation factor TFIID subunit 6 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
TOB1
Protein Tob1 |
1 |
12 |
Small-scale |
0.479 | High |
|
|
HCFC1
Host cell factor 1 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
HMGA2
High mobility group protein HMGI-C |
1 |
3 |
Small-scale |
0.479 | High |
|
|
TBA4A
Tubulin alpha-4A chain |
1 |
2 |
Small-scale |
0.479 | High |
|
|
RUNX1
Runt-related transcription factor 1 |
1 |
16 |
Small-scale |
0.479 | High |
|
|
SQSTM
Sequestosome-1 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
HDAC1
Histone deacetylase 1 |
1 |
12 |
Small-scale |
0.479 | High |
|
|
RUNX3
Runt-related transcription factor 3 |
1 |
16 |
Small-scale |
0.479 | High |
|
|
NCOA6
Nuclear receptor coactivator 6 |
1 |
8 |
Small-scale |
0.479 | High |
|
|
MED22
Mediator of RNA polymerase II transcription subunit 22 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
TAF5
Transcription initiation factor TFIID subunit 5 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
TGIF1
Homeobox protein TGIF1 |
1 |
11 |
Small-scale |
0.479 | High |
|
|
EZH2
Histone-lysine N-methyltransferase EZH2 |
1 |
11 |
Small-scale |
0.479 | High |
|
|
TAF3
Transcription initiation factor TFIID subunit 3 |
1 |
7 |
Small-scale |
0.479 | High |
|
|
MED25
Mediator of RNA polymerase II transcription subunit 25 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
DZIP3
E3 ubiquitin-protein ligase DZIP3 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
TF3C2
General transcription factor 3C polypeptide 2 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
KAT2A
Histone acetyltransferase KAT2A |
1 |
20 |
Small-scale |
0.479 | High |
|
|
ZN521
Zinc finger protein 521 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
BCL7B
B-cell CLL/lymphoma 7 protein family member B |
1 |
2 |
Small-scale |
0.479 | High |
|
|
FOXP3
Forkhead box protein P3 |
1 |
7 |
Small-scale |
0.479 | High |
|
|
CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
MED20
Mediator of RNA polymerase II transcription subunit 20 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
MED4
Mediator of RNA polymerase II transcription subunit 4 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
MED17
Mediator of RNA polymerase II transcription subunit 17 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
MED9
Mediator of RNA polymerase II transcription subunit 9 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
CXXC1
CXXC-type zinc finger protein 1 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2 |
1 |
8 |
Small-scale |
0.479 | High |
|
|
LEF1
Lymphoid enhancer-binding factor 1 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
MED16
Mediator of RNA polymerase II transcription subunit 16 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
CPNE3
Copine-3 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
TF3C5
General transcription factor 3C polypeptide 5 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
EWS
RNA-binding protein EWS |
1 |
8 |
High-throughput |
0.457 | High |
|
|
FA83G
Protein FAM83G |
1 |
2 |
Small-scale |
0.445 | High |
|
|
GPIX
Platelet glycoprotein IX |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q |
1 |
0 |
High-throughput |
0.265 | Low |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
