HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (p62)
Gene: SQSTM1

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 39098523
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008104 - intracellular protein localization GO:0038023 - signaling receptor activity and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 1084
+	Hs
		1107904 SQSTM_HUMAN (1-440): 0: 760: 100.00		AMOL1_HUMAN (1-912): 1.21e-43: 174: 44.28
+	Hs
		1108292 SQSTM_HUMAN (1-440): 0: 760: 100.00		CE164_HUMAN (20-1079): 7.9e-33: 140: 10.82
+	Hs
		1108235 SQSTM_HUMAN (1-440): 0: 760: 100.00		RRBP1_HUMAN (20-907): 1.89e-27: 123: 9.81
+	Hs
		1128734 NBR1_HUMAN (80-184): 5.97e-10: 63.6: 24.78		AMOT_HUMAN (1-1084): 2.95e-100: 343: 100.00
+	Hs
		1154121 MIB1_HUMAN (105-233): 3.49e-43: 164: 25.19		ITSN1_HUMAN (554-1077): 9.52e-10: 65.4: 8.75