Protein: DUS19
Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase TS-DSP1) (Low molecular weight dual specificity phosphatase 3) (LMW-DSP3) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1) (SAPK pathway-regulating phosphatase 1)

Gene: DUS19, DUSP19
Organism: Homo sapiens
Interactions: 95
UniProt ID: Q8WTR2

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0004860 - protein kinase inhibitor activity
GO:0005078 - MAP-kinase scaffold activity
GO:0005737 - cytoplasm
GO:0006469 - negative regulation of protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

153152

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

2

9

Small-scale

0.768

High

411449

INSR
Insulin receptor

1

20

High-throughput

0.698

High

435703

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.698

High

891921

ACTB
Actin, cytoplasmic 1

4

13

High-throughput

0.692

High

526427

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

7

3

High-throughput

0.686

High

915454

ACTA
Actin, aortic smooth muscle

3

12

High-throughput

0.667

High

1173743

ACD11
Acyl-CoA dehydrogenase family member 11

3

2

High-throughput

0.667

High

800927

MK09
Mitogen-activated protein kinase 9

1

20

Small-scale

0.647

High

213850

SYNC
Asparagine--tRNA ligase, cytoplasmic

3

0

High-throughput

0.638

High

1122454

ACTBL
Beta-actin-like protein 2

2

12

High-throughput

0.628

High

171315

EPHB6
Ephrin type-B receptor 6

1

20

High-throughput

0.625

High

665295

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.625

High

659006

MK01
Mitogen-activated protein kinase 1

1

20

High-throughput

0.618

High

1259405

DUS19
Dual specificity protein phosphatase 19

1

19

High-throughput

0.618

High

1259410

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

6

Small-scale

0.618

High

1259417

STK26
Serine/threonine-protein kinase 26

1

4

High-throughput

0.618

High

1259419

NRBP
Nuclear receptor-binding protein

1

3

High-throughput

0.618

High

149095

CTRO
Citron Rho-interacting kinase

1

4

High-throughput

0.553

High

1259408

AURKB
Aurora kinase B

1

4

High-throughput

0.553

High

338743

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.541

High

383896

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.541

High

729317

VGFR3
Vascular endothelial growth factor receptor 3

1

20

High-throughput

0.541

High

729673

VGFR2
Vascular endothelial growth factor receptor 2

1

13

High-throughput

0.541

High

968326

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

20

High-throughput

0.541

High

968440

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.541

High

518901

TPR
Nucleoprotein TPR

1

9

High-throughput

0.536

High

672222

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

4

High-throughput

0.536

High

929942

ACTG
Actin, cytoplasmic 2

1

12

High-throughput

0.536

High

930934

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

4

High-throughput

0.536

High

1085011

DREB
Drebrin

1

4

High-throughput

0.536

High

601956

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.494

High

1031156

PTK7
Inactive tyrosine-protein kinase 7

1

10

High-throughput

0.494

High

1070988

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.494

High

1219431

LMTK2
Serine/threonine-protein kinase LMTK2

1

20

High-throughput

0.494

High

1259421

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.494

High

927851

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

2

High-throughput

0.489

High

932028

TPM4
Tropomyosin alpha-4 chain

1

3

High-throughput

0.489

High

933025

ACTS
Actin, alpha skeletal muscle

1

9

High-throughput

0.489

High

1058695

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

1

High-throughput

0.489

High

1259420

COR1C
Coronin-1C

1

4

High-throughput

0.489

High

117427

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

2

High-throughput

0.479

High

499958

CH60
60 kDa heat shock protein, mitochondrial

1

5

High-throughput

0.479

High

548934

NDKA
Nucleoside diphosphate kinase A

1

6

High-throughput

0.479

High

568998

CAN2
Calpain-2 catalytic subunit

1

2

High-throughput

0.479

High

670848

PRDX5
Peroxiredoxin-5, mitochondrial

1

3

High-throughput

0.479

High

826543

DHYS
Deoxyhypusine synthase

1

1

High-throughput

0.479

High

842972

TCPQ
T-complex protein 1 subunit theta

1

6

High-throughput

0.479

High

893820

S10AA
Protein S100-A10

1

1

High-throughput

0.479

High

919654

RAP1A
Ras-related protein Rap-1A

1

7

High-throughput

0.479

High

929336

IF5A1
Eukaryotic translation initiation factor 5A-1

1

5

High-throughput

0.479

High

1039268

DCTN2
Dynactin subunit 2

1

2

High-throughput

0.479

High

1069292

2A5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

1

1

High-throughput

0.479

High

1072654

RHEB
GTP-binding protein Rheb

1

6

High-throughput

0.479

High

1190353

HDDC2
5'-deoxynucleotidase HDDC2

1

3

High-throughput

0.479

High

1190689

HDGR2
Hepatoma-derived growth factor-related protein 2

1

1

High-throughput

0.479

High

1244914

NUD10
Diphosphoinositol polyphosphate phosphohydrolase 3-alpha

1

2

High-throughput

0.479

High

1259409

PARK7
Parkinson disease protein 7

1

7

High-throughput

0.479

High

1259411

TCPH
T-complex protein 1 subunit eta

1

3

High-throughput

0.479

High

1259413

PFD4
Prefoldin subunit 4

1

1

High-throughput

0.479

High

1259414

ARL8B
ADP-ribosylation factor-like protein 8B

1

11

High-throughput

0.479

High

118891

GTPB1
GTP-binding protein 1

1

2

High-throughput

0.470

High

1059452

NAA30
N-alpha-acetyltransferase 30

1

0

High-throughput

0.458

High

1139664

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.458

High

1239465

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

1

0

High-throughput

0.458

High

242183

TI17B
Mitochondrial import inner membrane translocase subunit Tim17-B

1

5

High-throughput

0.437

High

385880

CPNS1
Calpain small subunit 1

1

5

High-throughput

0.437

High

525574

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

3

High-throughput

0.437

High

585974

SPEE
Spermidine synthase

1

6

High-throughput

0.437

High

708486

MCM4
DNA replication licensing factor MCM4

1

7

High-throughput

0.437

High

800602

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

6

High-throughput

0.437

High

803947

NSF
Vesicle-fusing ATPase

1

5

High-throughput

0.437

High

843306

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.437

High

845872

RAB13
Ras-related protein Rab-13

1

2

High-throughput

0.437

High

858189

BIEA
Biliverdin reductase A

1

1

High-throughput

0.437

High

950667

ARF5
ADP-ribosylation factor 5

1

10

High-throughput

0.437

High

1055595

MCM6
DNA replication licensing factor MCM6

1

7

High-throughput

0.437

High

1058494

GANAB
Neutral alpha-glucosidase AB

1

4

High-throughput

0.437

High

1061940

GAPD1
GTPase-activating protein and VPS9 domain-containing protein 1

1

3

High-throughput

0.437

High

1070876

RCN1
Reticulocalbin-1

1

5

High-throughput

0.437

High

1133442

UBR4
E3 ubiquitin-protein ligase UBR4

1

5

High-throughput

0.437

High

1259406

TCPW
T-complex protein 1 subunit zeta-2

1

4

High-throughput

0.437

High

1259407

AP3S1
AP-3 complex subunit sigma-1

1

8

High-throughput

0.437

High

1259412

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

2

High-throughput

0.437

High

1259415

CUED1
CUE domain-containing protein 1

1

1

High-throughput

0.437

High

1259416

TMOD3
Tropomodulin-3

1

3

High-throughput

0.437

High

1259418

MTFP1
Mitochondrial fission process protein 1

1

1

High-throughput

0.437

High

1259422

HIG1A
HIG1 domain family member 1A, mitochondrial

1

1

High-throughput

0.437

High

764400

FEN1
Flap endonuclease 1

3

0

High-throughput

0.347

High

612998

TCEA1
Transcription elongation factor A protein 1

2

0

High-throughput

0.318

High

49149

TM223
Transmembrane protein 223

1

0

High-throughput

0.249

Low

519243

KCRB
Creatine kinase B-type

1

0

High-throughput

0.249

Low

594936

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.249

Low

879700

ATPK
ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.249

Low

1204295

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024