HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (p62)
Gene: SQSTM1

Interactor 2: TRI50 (Q86XT4)
E3 ubiquitin-protein ligase TRIM50 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM50) (Tripartite motif-containing protein 50)
Gene: TRIM50

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22792322
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 487
+	Hs
		623327 SQSTM_HUMAN (1-440): 0: 760: 100.00		RO52_HUMAN (1-473): 4.58e-148: 433: 26.72
+	Hs
		571956 SQSTM_HUMAN (1-440): 0: 760: 100.00		TRI27_HUMAN (1-480): 3.9e-136: 404: 27.24
+	Hs
		1108032 SQSTM_HUMAN (1-440): 0: 760: 100.00		TRI11_HUMAN (1-482): 1.7e-131: 390: 26.43
+	Hs
		1108121 SQSTM_HUMAN (1-440): 0: 760: 100.00		TRIM5_HUMAN (1-475): 2.09e-112: 343: 25.00
+	Mm
		584838 SQSTM_MOUSE (1-440): 0: 731: 90.72		TR30A_MOUSE (1-475): 4.08e-101: 313: 21.57
+	Hs
		623345 NBR1_HUMAN (80-184): 5.97e-10: 63.6: 24.78		RO52_HUMAN (1-473): 4.58e-148: 433: 26.72