HitPredict

Interactor 1: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62) (p62)
Gene: SQSTM1

Interactor 2: MED15 (Q96RN5)
Mediator of RNA polymerase II transcription subunit 15 (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a) (Mediator complex subunit 15) (Positive cofactor 2 glutamine/Q-rich-associated protein) (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Trinucleotide repeat-containing gene 7 protein)
Gene: MED15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39098523
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 788
+	Hs
		169542 SQSTM_HUMAN (1-440): 0: 760: 100.00		HGS_HUMAN (71-479): 5.35e-23: 107: 18.08
+	Hs
		215922 SQSTM_HUMAN (1-440): 0: 760: 100.00		SYNJ1_HUMAN (199-609): 1.02e-13: 77.5: 10.77
+	Hs
		925714 SQSTM_HUMAN (1-440): 0: 760: 100.00		SC24C_HUMAN (278-546): 2.06e-12: 73.1: 14.71
+	Hs
		1107973 SQSTM_HUMAN (1-440): 0: 760: 100.00		TITIN_HUMAN (156-460): 3.24e-12: 72.7: 11.22
+	Hs
		1107921 SQSTM_HUMAN (1-440): 0: 760: 100.00		MINK1_HUMAN (117-608): 2.32e-09: 63.2: 15.25
+	Hs
		169635 MIB1_HUMAN (105-233): 3.49e-43: 164: 25.19		HGS_HUMAN (71-479): 5.35e-23: 107: 18.08
+	Hs
		1128792 NBR1_HUMAN (80-184): 5.97e-10: 63.6: 24.78		TITIN_HUMAN (156-460): 3.24e-12: 72.7: 11.22