HitPredict

Interactor 1: INAVA (Q3KP66)
Innate immunity activator protein
Gene: INAVA

Interactor 2: CYH2 (Q99418)
Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)
Gene: CYTH2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.719

Property	Details
Experiments	29420262, 28514442, 30355448, 33961781, 31022698
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 663 Hs			1 400
+	Hs
		1074102 INAVA_HUMAN (1-663): 0: 1010: 100.00		CYH1_HUMAN (2-397): 5.27e-176: 498: 83.08
+	Hs
		1108772 INAVA_HUMAN (1-663): 0: 1010: 100.00		CYH4_HUMAN (1-395): 2.55e-169: 480: 68.61
+	Hs
		212315 INAVA_HUMAN (1-663): 0: 1010: 100.00		CYH3_HUMAN (22-395): 4.03e-167: 475: 82.89
+	Hs
		1074121 FRM4B_HUMAN (85-373): 1.08e-106: 348: 31.89		CYH1_HUMAN (2-397): 5.27e-176: 498: 83.08
+	Mm
		140107 FRM4B_MOUSE (85-373): 3.83e-104: 341: 29.47		CYH3_MOUSE (22-395): 5.25e-165: 469: 82.09
+	Hs
		1074119 FRM4A_HUMAN (112-397): 2.82e-92: 309: 43.05		CYH1_HUMAN (2-397): 5.27e-176: 498: 83.08
+	Hs
		1350519 FRM4A_HUMAN (112-397): 2.82e-92: 309: 43.05		CYH4_HUMAN (1-395): 2.55e-169: 480: 68.61
+	Hs
		1293344 CC120_HUMAN (110-369): 7.2e-52: 191: 26.10		CYH2_HUMAN (1-400): 2.27e-180: 509: 100.00
+	Hs
		1074111 CC120_HUMAN (110-369): 7.2e-52: 191: 26.10		CYH1_HUMAN (2-397): 5.27e-176: 498: 83.08
+	Hs
		1293374 CC120_HUMAN (110-369): 7.2e-52: 191: 26.10		CYH4_HUMAN (1-395): 2.55e-169: 480: 68.61
+	Hs
		212320 CC120_HUMAN (110-369): 7.2e-52: 191: 26.10		CYH3_HUMAN (22-395): 4.03e-167: 475: 82.89