HitPredict

Interactor 1: HXB9 (P17482)
Homeobox protein Hox-B9 (Homeobox protein Hox-2.5) (Homeobox protein Hox-2E)
Gene: HOXB9

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29844126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 250 Hs			1 2517
+	Hs
		679011 HXC9_HUMAN (1-234): 1.05e-33: 124: 44.31		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		595628 HXA5_HUMAN (7-249): 5.95e-32: 119: 24.32		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		678805 HXA10_HUMAN (16-246): 4.22e-28: 112: 30.74		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		679050 HXD11_HUMAN (176-247): 4.42e-20: 89.4: 58.33		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		678875 HXA11_HUMAN (172-247): 4.67e-20: 89: 53.95		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		567820 HXB9_HUMAN (1-250): 5.95e-59: 188: 100.00		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		595592 HXA5_HUMAN (7-249): 5.95e-32: 119: 24.32		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Mm
		446925 HXA5_MOUSE (7-249): 1.2e-31: 119: 24.32		Q60I23_MOUSE (1102-1308): 2.84e-56: 201: 27.40
+	Mm
		192289 ALX4_MOUSE (2-250): 4.49e-30: 117: 18.22		SOX2_MOUSE (1102-1308): 3.32e-55: 198: 26.44
+	Hs
		882171 GSC_HUMAN (13-245): 6.77e-34: 124: 20.60		SOX13_HUMAN (867-1226): 1.83e-47: 184: 24.66
+	Dm
		950090 UBX_DROME (39-246): 5.08e-29: 114: 25.24		Q9VUD3_DROME (1098-1222): 6.97e-40: 160: 27.78
+	Ce
		712506 LIN39_CAEEL (60-249): 2.11e-33: 123: 29.08		POP1_CAEEL (959-1182): 1.17e-34: 141: 22.17
+	Hs
		174010 SHOX_HUMAN (164-249): 8.53e-30: 114: 31.40		SOX6_HUMAN (887-1289): 5.1e-35: 148: 16.28
+	Hs
		727714 GSC_HUMAN (13-245): 6.77e-34: 124: 20.60		SOX5_HUMAN (833-1211): 2.27e-29: 129: 17.71
+	Hs
		174009 SHOX_HUMAN (164-249): 8.53e-30: 114: 31.40		SOX5_HUMAN (833-1211): 2.27e-29: 129: 17.71
+	Dm
		668228 ABDA_DROME (186-242): 9.51e-17: 80.9: 70.18		SOX15_DROME (954-1301): 3.81e-36: 151: 20.34
+	Dm
		115538 UBX_DROME (39-246): 5.08e-29: 114: 25.24		M9PFG6_DROME (1092-1190): 2.16e-26: 116: 32.32
+	Hs
		882174 GSC_HUMAN (13-245): 6.77e-34: 124: 20.60		NCOR2_HUMAN (290-1816): 8.11e-14: 80.2: 8.06
+	Dm
		115535 ABDA_DROME (186-242): 9.51e-17: 80.9: 70.18		M9PFG6_DROME (1092-1190): 2.16e-26: 116: 32.32
+	Hs
		882142 GSC_HUMAN (13-245): 6.77e-34: 124: 20.60		KMT2C_HUMAN (1873-2516): 1.5e-09: 66.4: 10.57