HitPredict

Interactor 1: K2C71 (Q3SY84)
Keratin, type II cytoskeletal 71 (Cytokeratin-71) (CK-71) (Keratin-71) (K71) (Type II inner root sheath-specific keratin-K6irs1) (Keratin 6 irs) (hK6irs) (hK6irs1) (Type-II keratin Kb34)
Gene: KRT71

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27591049
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 523 Hs			1 956
+	Hs
		380696 K2C1_HUMAN (96-458): 5.13e-162: 476: 67.77		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1192468 K2C1B_HUMAN (43-461): 1.97e-160: 469: 57.66		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		729179 K22E_HUMAN (102-447): 4.34e-154: 456: 68.21		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		444557 K2C7_HUMAN (62-457): 5.63e-136: 403: 60.10		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		409246 K2C8_HUMAN (102-466): 3.3e-135: 402: 61.14		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1343331 KRT84_HUMAN (1-458): 8.03e-100: 314: 47.67		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1062069 K2C72_HUMAN (1-523): 2.93e-85: 274: 70.48		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		531636 K2C5_HUMAN (1-453): 6.41e-82: 267: 56.82		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		380523 K2C6B_HUMAN (2-462): 9.76e-81: 264: 57.61		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		359537 K2C6A_HUMAN (2-462): 3.17e-77: 255: 57.40		CYLD_HUMAN (1-956): 0: 1872: 100.00