Interactor 1: STING (Q3TBT3)
Stimulator of interferon genes protein (mSTING) (Endoplasmic reticulum interferon stimulator) (ERIS) (Mediator of IRF3 activation) (MMITA) (Transmembrane protein 173)
Gene: Sting1

Interactor 2: TBK1 (Q9WUN2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.740

The method score is based on:

Property Details
Experiments 33086059, 32678307, 32554809, 22728658, 23028052, 22000020, 23142775
Identification Methods affinity chromatography technology, proximity labelling technology, protein kinase assay, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002218 - activation of innate immune response
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010468 - regulation of gene expression
and 5 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 378
Mm

1 729
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm

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Last updated: 15 Jul 2024