HitPredict

Interactor 1: PRC2C (Q3TLH4)
Protein PRRC2C (BAT2 domain-containing protein 1) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)
Gene: Prrc2c

Interactor 2: FXR1 (Q61584)
RNA-binding protein FXR1 (FXR1P) (mFxr1p)
Gene: FXR1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2846 Mm			1 677
+	Hs
		843980 PRC2C_HUMAN (1-2846): 0: 655: 83.20		FXR1_HUMAN (1-677): 0: 995: 88.33
+	Hs
		844303 PRC2C_HUMAN (1-2846): 0: 655: 83.20		FXR2_HUMAN (4-656): 0: 851: 64.06
+	Mm
		1111989 PRC2C_MOUSE (1-2846): 0: 763: 100.00		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Mm
		1142852 PRC2B_MOUSE (1-1518): 1.93e-54: 213: 19.44		FXR1_MOUSE (1-677): 0: 1073: 100.00
+	Hs
		843719 PRC2B_HUMAN (1-2154): 2.34e-57: 223: 14.25		FXR1_HUMAN (1-677): 0: 995: 88.33
+	Mm
		1142913 NCOR2_MOUSE (688-2838): 9.89e-31: 136: 8.04		FXR1_MOUSE (1-677): 0: 1073: 100.00
+	Hs
		820851 PRC2A_HUMAN (673-2845): 2.61e-34: 148: 8.78		FXR1_HUMAN (1-677): 0: 995: 88.33
+	Hs
		844097 PRC2B_HUMAN (1-2154): 2.34e-57: 223: 14.25		FXR2_HUMAN (4-656): 0: 851: 64.06
+	Hs
		820852 PRC2A_HUMAN (673-2845): 2.61e-34: 148: 8.78		FXR2_HUMAN (4-656): 0: 851: 64.06
+	Mm
		729462 PRC2C_MOUSE (1-2846): 0: 763: 100.00		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80
+	Hs
		989216 PRC2C_HUMAN (1-2846): 0: 655: 83.20		FMR1_HUMAN (300-461): 3.4e-48: 181: 56.10
+	Mm
		1186627 PRC2B_MOUSE (1-1518): 1.93e-54: 213: 19.44		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Mm
		57191 CHD7_MOUSE (90-665): 7.2e-38: 159: 13.95		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Mm
		1207112 NCOR2_MOUSE (688-2838): 9.89e-31: 136: 8.04		Q8BPK8_MOUSE (1-334): 0: 622: 73.65
+	Hs
		988930 PRC2B_HUMAN (1-2154): 2.34e-57: 223: 14.25		FMR1_HUMAN (300-461): 3.4e-48: 181: 56.10
+	Mm
		729531 PRC2B_MOUSE (1-1518): 1.93e-54: 213: 19.44		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80
+	Mm
		57183 CHD7_MOUSE (90-665): 7.2e-38: 159: 13.95		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80
+	Hs
		820894 PRC2A_HUMAN (673-2845): 2.61e-34: 148: 8.78		FMR1_HUMAN (300-461): 3.4e-48: 181: 56.10
+	Mm
		729608 NCOR2_MOUSE (688-2838): 9.89e-31: 136: 8.04		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80
+	Mm
		729533 PRC2A_MOUSE (1167-2839): 1.05e-25: 119: 8.78		FMR1_MOUSE (219-461): 1.28e-49: 184: 42.80