HitPredict

Interactor 1: DDB1 (Q3U1J4)
DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)
Gene: DDB1

Interactor 2: DCAF5 (Q80T85)
DDB1- and CUL4-associated factor 5 (WD repeat-containing protein 22)
Gene: DCAF5

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34161765
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1140 Mm			1 946
+	Hs
		1082337 DDB1_HUMAN (1-1140): 0: 1445: 99.65		DCAF5_HUMAN (1-946): 0: 723: 89.99
+	Hs
		473600 DDB1_HUMAN (1-1140): 0: 1445: 99.65		DC8L2_HUMAN (3-389): 1.63e-84: 286: 21.32
+	Mm
		1112284 DDB1_MOUSE (1-1140): 0: 1446: 100.00		DCAF8_MOUSE (3-377): 9.38e-81: 275: 21.47
+	Hs
		1082225 DDB1_HUMAN (1-1140): 0: 1445: 99.65		DCAF8_HUMAN (3-377): 2.35e-80: 274: 21.21
+	Hs
		245605 DDB1_HUMAN (1-1140): 0: 1445: 99.65		TBL1X_HUMAN (222-553): 3.65e-36: 147: 10.34
+	Hs
		1082374 DDB1_HUMAN (1-1140): 0: 1445: 99.65		TBL1R_HUMAN (228-549): 1.06e-35: 144: 9.77
+	At
		1340744 DDB1A_ARATH (2-1140): 0: 1254: 52.18		Q9M1E5_ARATH (36-362): 3.65e-96: 313: 25.80
+	At
		221833 DDB1B_ARATH (3-1140): 0: 1248: 51.00		Q9M1E5_ARATH (36-362): 3.65e-96: 313: 25.80
+	Zm
		37968 A0A1D6ME60_MAIZE (3-1140): 0: 1244: 52.57		B4FRU9_MAIZE (18-386): 1.1e-94: 309: 22.20
+	Mm
		1112265 DDB1_MOUSE (1-1140): 0: 1446: 100.00		WDTC1_MOUSE (46-218): 7.18e-14: 77.8: 32.04
+	Hs
		1082281 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDTC1_HUMAN (46-218): 6.26e-14: 78.2: 32.04
+	Hs
		1082327 DDB1_HUMAN (1-1140): 0: 1445: 99.65		SNR40_HUMAN (320-538): 1.49e-12: 72.1: 14.16
+	Hs
		1082263 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5B_HUMAN (1-81): 5.16e-11: 67.2: 15.66
+	Hs
		903254 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5_HUMAN (1-84): 3.35e-10: 64.5: 15.12
+	At
		95049 DDB1A_ARATH (2-1140): 0: 1254: 52.18		KTN82_ARATH (2-173): 3.75e-32: 137: 17.92
+	At
		95047 DDB1B_ARATH (3-1140): 0: 1248: 51.00		KTN82_ARATH (2-173): 3.75e-32: 137: 17.92
+	At
		1114755 DDB1A_ARATH (2-1140): 0: 1254: 52.18		PRL1_ARATH (13-260): 6.75e-19: 92.9: 17.80
+	At
		221824 DDB1B_ARATH (3-1140): 0: 1248: 51.00		PRL1_ARATH (13-260): 6.75e-19: 92.9: 17.80
+	At
		186951 DDB1A_ARATH (2-1140): 0: 1254: 52.18		MSI3_ARATH (49-219): 5.78e-09: 61.2: 25.86
+	At
		186950 DDB1B_ARATH (3-1140): 0: 1248: 51.00		MSI3_ARATH (49-219): 5.78e-09: 61.2: 25.86