HitPredict

Interactor 1: DDB1 (Q3U1J4)
DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)
Gene: DDB1

Interactor 2: WDTC1 (Q80ZK9)
WD and tetratricopeptide repeats protein 1
Gene: WDTC1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	27113764, 34161765
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1140 Mm			1 677
+	Hs
		1082281 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDTC1_HUMAN (1-677): 6.84e-131: 403: 96.76
+	Mm
		1112305 DDB1_MOUSE (1-1140): 0: 1446: 100.00		DCAF6_MOUSE (422-669): 4.75e-49: 186: 24.81
+	Hs
		1016284 DDB1_HUMAN (1-1140): 0: 1445: 99.65		TBL3_HUMAN (101-661): 3.43e-49: 186: 11.05
+	Hs
		1082217 DDB1_HUMAN (1-1140): 0: 1445: 99.65		DCAF6_HUMAN (221-669): 2.02e-44: 172: 17.03
+	Hs
		1040799 DDB1_HUMAN (1-1140): 0: 1445: 99.65		PWP1_HUMAN (9-214): 7.16e-36: 143: 21.26
+	Hs
		1082225 DDB1_HUMAN (1-1140): 0: 1445: 99.65		DCAF8_HUMAN (511-677): 6.45e-33: 136: 26.80
+	Hs
		858628 DDB1_HUMAN (1-1140): 0: 1445: 99.65		PPP5_HUMAN (346-513): 4.01e-33: 135: 28.26
+	Hs
		473600 DDB1_HUMAN (1-1140): 0: 1445: 99.65		DC8L2_HUMAN (511-677): 3.3e-32: 134: 28.50
+	Hs
		1082263 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5B_HUMAN (446-654): 1.75e-19: 92.2: 16.90
+	Mm
		1112258 DDB1_MOUSE (1-1140): 0: 1446: 100.00		DCAF5_MOUSE (526-623): 6.28e-10: 64.5: 31.25
+	Hs
		1082327 DDB1_HUMAN (1-1140): 0: 1445: 99.65		SNR40_HUMAN (572-663): 1.62e-10: 65.2: 20.20
+	Hs
		1082337 DDB1_HUMAN (1-1140): 0: 1445: 99.65		DCAF5_HUMAN (526-623): 4.09e-10: 65.2: 31.25
+	Mm
		1112284 DDB1_MOUSE (1-1140): 0: 1446: 100.00		DCAF8_MOUSE (22-212): 2.72e-09: 62.2: 12.44
+	Hs
		903254 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5_HUMAN (569-674): 2.11e-09: 61.8: 12.50
+	At
		1340744 DDB1A_ARATH (2-1140): 0: 1254: 52.18		Q9M1E5_ARATH (263-670): 1.56e-40: 156: 18.55
+	At
		221833 DDB1B_ARATH (3-1140): 0: 1248: 51.00		Q9M1E5_ARATH (263-670): 1.56e-40: 156: 18.55
+	Zm
		37968 A0A1D6ME60_MAIZE (3-1140): 0: 1244: 52.57		B4FRU9_MAIZE (508-627): 4.26e-34: 138: 31.41
+	At
		1114755 DDB1A_ARATH (2-1140): 0: 1254: 52.18		PRL1_ARATH (518-615): 1.79e-10: 65.7: 18.37
+	At
		221824 DDB1B_ARATH (3-1140): 0: 1248: 51.00		PRL1_ARATH (518-615): 1.79e-10: 65.7: 18.37
+	Hs
		1073126 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		Q9BPW0_HUMAN (346-513): 5.41e-33: 134: 28.26