HitPredict

Interactor 1: DDB1 (Q3U1J4)
DNA damage-binding protein 1 (DDB p127 subunit) (Damage-specific DNA-binding protein 1) (UV-damaged DNA-binding factor)
Gene: DDB1

Interactor 2: DCA11 (Q91VU6)
DDB1- and CUL4-associated factor 11 (WD repeat-containing protein 23)
Gene: Dcaf11

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34161765
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0005654 - nucleoplasm GO:0016567 - protein ubiquitination GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1140 Mm			1 549
+	Hs
		1016284 DDB1_HUMAN (1-1140): 0: 1445: 99.65		TBL3_HUMAN (89-548): 1.16e-70: 243: 11.92
+	Hs
		1082374 DDB1_HUMAN (1-1140): 0: 1445: 99.65		TBL1R_HUMAN (2-435): 1.43e-68: 231: 14.22
+	Hs
		903254 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5_HUMAN (51-382): 1.18e-62: 210: 15.73
+	Hs
		245605 DDB1_HUMAN (1-1140): 0: 1445: 99.65		TBL1X_HUMAN (7-339): 4.93e-54: 193: 11.70
+	Hs
		1082263 DDB1_HUMAN (1-1140): 0: 1445: 99.65		WDR5B_HUMAN (340-548): 1.1e-46: 168: 16.82
+	Hs
		1082295 DDB1_HUMAN (1-1140): 0: 1445: 99.65		DCA11_HUMAN (98-402): 2.98e-35: 141: 11.14
+	Hs
		1082327 DDB1_HUMAN (1-1140): 0: 1445: 99.65		SNR40_HUMAN (7-244): 5.13e-26: 111: 11.38
+	Mm
		1112307 DDB1_MOUSE (1-1140): 0: 1446: 100.00		SKI8_MOUSE (186-384): 4.46e-09: 60.1: 29.70
+	Hs
		1082381 DDB1_HUMAN (1-1140): 0: 1445: 99.65		SKI8_HUMAN (186-384): 3.62e-09: 60.1: 29.70
+	Hs
		1073094 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		FBXW7_HUMAN (17-464): 7.09e-76: 255: 15.01
+	At
		1340746 DDB1A_ARATH (2-1140): 0: 1254: 52.18		VIP3_ARATH (268-393): 5.48e-12: 68.9: 27.78
+	At
		95049 DDB1A_ARATH (2-1140): 0: 1254: 52.18		KTN82_ARATH (306-525): 1.06e-09: 63.5: 22.27
+	At
		221835 DDB1B_ARATH (3-1140): 0: 1248: 51.00		VIP3_ARATH (268-393): 5.48e-12: 68.9: 27.78
+	At
		1228206 DDB1A_ARATH (2-1140): 0: 1254: 52.18		Q8LPI5_ARATH (31-262): 3.91e-09: 61.1: 13.45
+	At
		1114755 DDB1A_ARATH (2-1140): 0: 1254: 52.18		PRL1_ARATH (217-385): 3.97e-09: 60.8: 27.81
+	At
		95047 DDB1B_ARATH (3-1140): 0: 1248: 51.00		KTN82_ARATH (306-525): 1.06e-09: 63.5: 22.27
+	At
		221824 DDB1B_ARATH (3-1140): 0: 1248: 51.00		PRL1_ARATH (217-385): 3.97e-09: 60.8: 27.81
+	Hs
		1073168 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		NLE1_HUMAN (10-245): 7.35e-29: 121: 12.55
+	Hs
		1073144 SF3B3_HUMAN (3-1126): 0: 1097: 21.25		SKI8_HUMAN (186-384): 3.62e-09: 60.1: 29.70
+	Ce
		953809 DDB1_CAEEL (1-1140): 0: 1010: 37.04		DCA11_CAEEL (247-541): 1.25e-16: 85.1: 11.80