HitPredict

Interactor 1: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Interactor 2: Q4VA93 (Q4VA93)
Protein kinase C (EC 2.7.11.13)
Gene: Prkca

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28706196
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ank_2~Pkinase, C1_1~Ras, Pkinase~Ras
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1186 Mm			1 672
+	Mm
		593482 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		KPCA_MOUSE (1-672): 0: 787: 98.81
+	Mm
		934623 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		KPCB_MOUSE (1-664): 0: 741: 79.34
+	Mm
		930565 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		KPCG_MOUSE (20-670): 0: 695: 70.45
+	Mm
		554904 AGAP2_MOUSE (1-1186): 0: 1024: 100.00		KPCE_MOUSE (8-664): 0: 628: 44.61
+	Hs
		681996 AGAP2_HUMAN (1-1147): 0: 987: 94.10		AKT1_HUMAN (240-660): 9.14e-157: 462: 37.22
+	Dm
		1213373 CEG1A_DROME (384-1131): 2.93e-178: 552: 39.33		AKT1_DROME (148-658): 7.64e-151: 452: 31.93
+	Hs
		566393 ACAP1_HUMAN (614-1104): 5.16e-25: 114: 13.81		KPCA_HUMAN (1-672): 0: 794: 99.41
+	Rn
		1144344 GIT1_RAT (932-1139): 1.69e-71: 257: 32.88		AKT3_RAT (222-660): 5.28e-156: 460: 36.40
+	Hs
		681853 ACAP1_HUMAN (614-1104): 5.16e-25: 114: 13.81		AKT1_HUMAN (240-660): 9.14e-157: 462: 37.22