Protein: CSN5
COP9 signalosome complex subunit 5 (Signalosome subunit 5) (EC 3.4.-.-) (JAB1 homolog)

Gene: CSN5, csn-5
Organism: Caenorhabditis elegans
Interactions: 70
UniProt ID: P91001

Gene Ontology (top 5):
GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006508 - proteolysis
GO:0008180 - COP9 signalosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

759901

GLH1
ATP-dependent RNA helicase glh-1

3

14

Small-scale

0.669

High

1018854

Q23482
Uncharacterized protein

3

0

High-throughput

0.628

High

1018835

CSN5
COP9 signalosome complex subunit 5

1

17

Small-scale

0.618

High

1018841

CUL3
Cullin-3

1

15

Small-scale

0.618

High

1018860

CSN6
COP9 signalosome complex subunit 6

1

20

Small-scale

0.618

High

1018862

CSN1
COP9 signalosome complex subunit 1

2

20

Small-scale

0.600

High

1018850

APR1
Adenomatous polyposis coli protein-related protein 1

2

1

High-throughput

0.594

High

1018845

Q18477
Histone deacetylase 11

3

4

High-throughput

0.580

High

759647

IF5A1
Eukaryotic translation initiation factor 5A-1

2

3

High-throughput

0.576

High

1018836

SPD5
Spindle-defective protein 5

2

2

High-throughput

0.576

High

1018868

LIS1
Lissencephaly-1 homolog

2

5

High-throughput

0.576

High

145192

GLH3
ATP-dependent RNA helicase glh-3

1

14

Small-scale

0.573

High

1018847

UNC98
Zinc finger protein unc-98

1

2

Small-scale

0.552

High

1018838

DCTN2
Probable dynactin subunit 2

2

0

High-throughput

0.551

High

113074

BIR1
Chromosomal passenger complex protein bir-1

1

4

High-throughput

0.541

High

113504

G5EFS1
Death domain-containing protein

1

6

High-throughput

0.541

High

814429

MPK1
Mitogen-activated protein kinase mpk-1

1

4

High-throughput

0.541

High

861345

KLC
Kinesin light chain

1

2

High-throughput

0.541

High

1018837

SMA2
Dwarfin sma-2

1

5

High-throughput

0.541

High

1018842

PMK1
Mitogen-activated protein kinase pmk-1

1

7

High-throughput

0.541

High

1018843

Q17522
Cysteine-rich protein 1

1

5

High-throughput

0.541

High

1018849

APC11
Anaphase-promoting complex subunit 11

1

3

High-throughput

0.541

High

1018853

MIG15
Serine/threonine-protein kinase mig-15

1

8

High-throughput

0.541

High

1018857

PMK2
Mitogen-activated protein kinase pmk-2

1

8

High-throughput

0.541

High

1018867

STAT1
Signal transducer and activator of transcription 1

1

3

High-throughput

0.541

High

1018869

Q9NGT3
Mitotic spindle assembly checkpoint protein MAD2A

1

2

High-throughput

0.541

High

1018839

FBF2
Fem-3 mRNA-binding factor 2

1

5

Small-scale

0.527

High

1018866

FBF1
Fem-3 mRNA-binding factor 1

1

5

Small-scale

0.527

High

1018846

MEL28
Protein mel-28

2

5

High-throughput

0.526

High

1018865

SEC13
Protein SEC13 homolog

2

9

High-throughput

0.526

High

1018873

RS15
Small ribosomal subunit protein uS19

2

2

High-throughput

0.526

High

1018875

Q9XWK3
Nucleoporin p58/p45

2

3

High-throughput

0.526

High

1018874

TYDP2
5'-tyrosyl-DNA phosphodiesterase

1

0

High-throughput

0.518

High

1018789

HMP1
Alpha-catenin-like protein hmp-1

1

4

High-throughput

0.515

High

1018844

Q18239
DiSHevelled related

1

8

High-throughput

0.512

High

1018859

Q95PW9
NCK

1

10

High-throughput

0.508

High

1018861

Q95XA9
SH2 domain-containing protein

1

3

High-throughput

0.508

High

1018871

Q9U2T9
Intersectin-1

1

10

High-throughput

0.508

High

304038

O76566
CRE-UNC-96 protein

1

0

Small-scale

0.504

High

1018852

ERH
Enhancer of rudimentary homolog

1

1

High-throughput

0.494

High

109069

G4RZC8
PID domain-containing protein

1

0

High-throughput

0.486

High

112771

G5EEQ7
SH3 domain-containing protein

1

1

High-throughput

0.481

High

303983

RENT1
Regulator of nonsense transcripts 1

1

5

Small-scale

0.481

High

1018848

Q19641
Cysteine-rich protein 1

1

5

Small-scale

0.481

High

1018872

Q9U3B9
Nucleoporin Nup54 alpha-helical domain-containing protein

1

4

High-throughput

0.481

High

144586

CSN2
COP9 signalosome complex subunit 2

1

20

Small-scale

0.479

High

1018858

EIF3M
COP9/Signalosome and eIF3 complex-shared subunit 1

1

20

Small-scale

0.479

High

1018863

CSN4
COP9 signalosome complex subunit 4

1

15

Small-scale

0.479

High

1018864

CSN3
COP9 signalosome complex subunit 3

1

13

Small-scale

0.479

High

1018870

Q9TXM1
Uncharacterized protein

1

4

High-throughput

0.479

High

144705

STAM1
Signal transducing adapter molecule 1

1

8

High-throughput

0.464

High

784912

LEC1
32 kDa beta-galactoside-binding lectin

1

2

High-throughput

0.464

High

63564

A5JYX3
Vinculin

1

2

High-throughput

0.457

High

110887

G5ECK4
SH3 domain-containing GRB2-like protein

1

10

High-throughput

0.457

High

111220

DLG1
Disks large homolog 1

1

3

High-throughput

0.457

High

1018851

Q21295
Nucleoporin Nup54 alpha-helical domain-containing protein

1

3

High-throughput

0.457

High

1018876

LAG1
Suppressor of hairless protein homolog

1

2

High-throughput

0.457

High

109090

G4S034
Spectrin alpha chain

1

8

Small-scale

0.439

High

115340

H2KZ17
DiSHevelled related

1

5

High-throughput

0.439

High

232504

O44490
ELKS/RAB6-interacting/CAST family member 2

1

6

High-throughput

0.437

High

73218

B1Q240
DiSHevelled related

1

8

High-throughput

0.417

High

73282

SH3GH
Endophilin-A homolog

1

10

High-throughput

0.417

High

111818

NHRF1
Na(+)/H(+) exchange regulatory cofactor-like protein nrfl-1

1

8

High-throughput

0.417

High

234348

O45904
Galectin

1

2

High-throughput

0.417

High

1018855

Q33BL4
Protein kinase domain-containing protein

1

5

High-throughput

0.417

High

759475

YMX1
Uncharacterized protein K06H7.1

2

0

High-throughput

0.300

High

1018840

NUP35
Nucleoporin NUP35

2

0

High-throughput

0.300

High

1018856

NDC1
Nucleoporin ndc-1

2

0

High-throughput

0.300

High

72180

PLIN1
Perilipin-1 homolog

1

0

Small-scale

0.251

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025