HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: RYR3 (Q15413)
Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)
Gene: RYR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37788672
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 4870
+	Hs
		1112499 CUL1_HUMAN (18-768): 0: 709: 30.57		RYR3_HUMAN (1-4870): 0: 7847: 100.00
+	Hs
		1113954 CUL3_HUMAN (1-768): 0: 943: 100.00		RSPRY_HUMAN (970-1298): 2.28e-73: 260: 20.47
+	Hs
		1113466 CUL3_HUMAN (1-768): 0: 943: 100.00		RBP10_HUMAN (1010-1330): 6.18e-57: 213: 16.67
+	Hs
		1114079 CUL3_HUMAN (1-768): 0: 943: 100.00		RANB9_HUMAN (1010-1330): 9.46e-54: 206: 16.36
+	Hs
		1113365 CUL3_HUMAN (1-768): 0: 943: 100.00		RN123_HUMAN (1011-1226): 1.2e-47: 191: 20.64
+	Hs
		1113865 CUL3_HUMAN (1-768): 0: 943: 100.00		DDX1_HUMAN (1019-1226): 1.28e-44: 178: 18.69
+	Hs
		1113229 CUL3_HUMAN (1-768): 0: 943: 100.00		HNRL2_HUMAN (1076-1205): 9.51e-27: 122: 26.90
+	Hs
		1114905 CUL4A_HUMAN (10-768): 0: 801: 38.32		RBP10_HUMAN (1010-1330): 6.18e-57: 213: 16.67
+	Hs
		1114965 CUL4A_HUMAN (10-768): 0: 801: 38.32		DDX1_HUMAN (1019-1226): 1.28e-44: 178: 18.69
+	Hs
		1115328 CUL4B_HUMAN (5-768): 0: 796: 36.77		DDX1_HUMAN (1019-1226): 1.28e-44: 178: 18.69
+	Hs
		1112627 CUL1_HUMAN (18-768): 0: 709: 30.57		DDX1_HUMAN (1019-1226): 1.28e-44: 178: 18.69
+	Hs
		1112934 CUL2_HUMAN (30-768): 0: 673: 26.17		DDX1_HUMAN (1019-1226): 1.28e-44: 178: 18.69
+	Hs
		1363291 CUL5_HUMAN (25-768): 0: 597: 23.77		DDX1_HUMAN (1019-1226): 1.28e-44: 178: 18.69