Protein: RYR3
Ryanodine receptor 3 (RYR-3) (RyR3) (Brain ryanodine receptor-calcium release channel) (Brain-type ryanodine receptor) (Type 3 ryanodine receptor)

Gene: RYR3
Organism: Homo sapiens
Interactions: 25
UniProt ID: Q15413

Gene Ontology (top 5):
GO:0005219 - ryanodine-sensitive calcium-release channel activity
GO:0005509 - calcium ion binding
GO:0005516 - calmodulin binding
GO:0005790 - smooth endoplasmic reticulum
GO:0006816 - calcium ion transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

986853

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

2

9

Small-scale

0.778

High

721157

SORCN
Sorcin

1

7

Small-scale

0.647

High

996418

FKB1B
Peptidyl-prolyl cis-trans isomerase FKBP1B

1

9

Small-scale

0.647

High

1148270

RYR2
Ryanodine receptor 2

1

16

Small-scale

0.618

High

255036

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.575

High

1060171

B2CL1
Bcl-2-like protein 1

1

5

Small-scale

0.523

High

1092435

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

3

High-throughput

0.494

High

1112499

CUL1
Cullin-1

1

13

High-throughput

0.489

High

321543

PRP6
Pre-mRNA-processing factor 6

1

4

High-throughput

0.479

High

445895

ENOA
Alpha-enolase

1

2

High-throughput

0.479

High

532602

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

563807

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.479

High

1113174

CUL3
Cullin-3

1

13

High-throughput

0.479

High

1148272

RTN4
Reticulon-4

1

2

High-throughput

0.470

High

1148269

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

241758

PRKN
E3 ubiquitin-protein ligase parkin

1

10

High-throughput

0.437

High

587673

DESP
Desmoplakin

1

19

High-throughput

0.437

High

765545

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.437

High

934650

TERA
Transitional endoplasmic reticulum ATPase

1

7

Small-scale

0.437

High

942490

DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

1

4

High-throughput

0.437

High

951687

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

Small-scale

0.437

High

1148271

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

2

High-throughput

0.437

High

635189

HNF1A
Hepatocyte nuclear factor 1-alpha

1

0

High-throughput

0.292

High

1148273

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

0

High-throughput

0.269

Low

127088

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025