HitPredict

Interactor 1: CAS1 (Q46896)
CRISPR-associated endonuclease Cas1 (EC 3.1.-.-)
Gene: ygbT

Interactor 2: CAS1 (Q46896)
CRISPR-associated endonuclease Cas1 (EC 3.1.-.-)
Gene: ygbT

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.90	0.775

The method score is based on:

Property	Details
Experiments	24561554, 24793649
Identification Methods	two hybrid, molecular sieving, cosedimentation in solution, two hybrid array
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Cas_Cas1~Cas_Cas1
Common GO terms	GO:0003677 - DNA binding GO:0005737 - cytoplasm GO:0006281 - DNA repair GO:0006974 - DNA damage response GO:0008821 - crossover junction DNA endonuclease activity and 6 others more... GO:0017108 - 5'-flap endonuclease activity GO:0042803 - protein homodimerization activity GO:0043571 - maintenance of CRISPR repeat elements GO:0046872 - metal ion binding GO:0051607 - defense response to virus GO:0099048 - CRISPR-cas system
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024