HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: ANR28 (Q505D1)
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (PP6-ARS-A) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A) (Ankyrin repeat domain-containing protein 28) (Phosphatase interactor targeting protein hnRNP K) (PITK)
Gene: Ankrd28

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank~Ank_2, Ank_2~Ank_2, Ank_2~Ank_4
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1730 Mm			1 1053
+	Mm
		1116022 SHAN3_MOUSE (1-1730): 0: 626: 100.00		ANK2_MOUSE (1-672): 1.35e-171: 561: 28.07
+	Hs
		166969 ANR44_HUMAN (2-537): 4.52e-90: 319: 14.66		ANR28_HUMAN (1-876): 0: 573: 28.85
+	Hs
		167014 TNKS2_HUMAN (1-544): 1.02e-87: 315: 15.16		ANR28_HUMAN (1-876): 0: 573: 28.85
+	Hs
		862028 DAPK1_HUMAN (17-450): 1.03e-87: 318: 15.97		ANK2_HUMAN (1-672): 6.63e-173: 564: 28.49
+	Mm
		103608 ANK3_MOUSE (41-592): 7.79e-85: 311: 15.58		ANK2_MOUSE (1-672): 1.35e-171: 561: 28.07
+	Hs
		166869 TNKS1_HUMAN (12-400): 2.92e-79: 291: 16.63		ANR28_HUMAN (1-876): 0: 573: 28.85
+	Hs
		166971 ANR52_HUMAN (14-494): 3.38e-78: 284: 16.60		ANR28_HUMAN (1-876): 0: 573: 28.85
+	Mm
		103600 SHAN3_MOUSE (1-1730): 0: 626: 100.00		ANK3_MOUSE (746-1052): 3.19e-57: 218: 18.45
+	Hs
		166919 ANK3_HUMAN (12-592): 2.9e-68: 258: 15.01		ANR28_HUMAN (1-876): 0: 573: 28.85
+	Hs
		965154 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		ANK2_HUMAN (1-672): 6.63e-173: 564: 28.49
+	Hs
		883487 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		ANK2_HUMAN (1-672): 6.63e-173: 564: 28.49
+	Hs
		167036 ANR50_HUMAN (197-1044): 5.47e-49: 194: 10.39		ANR28_HUMAN (1-876): 0: 573: 28.85
+	Hs
		166849 ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60		ANR28_HUMAN (1-876): 0: 573: 28.85
+	Hs
		1021462 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		ANK3_HUMAN (445-1052): 1.88e-133: 449: 23.90
+	Hs
		883496 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		ANK3_HUMAN (445-1052): 1.88e-133: 449: 23.90
+	Hs
		1237559 ANR44_HUMAN (2-537): 4.52e-90: 319: 14.66		ANFY1_HUMAN (2-547): 3.07e-78: 281: 22.55
+	Hs
		1329533 TNKS2_HUMAN (1-544): 1.02e-87: 315: 15.16		TNKS2_HUMAN (1-334): 3.38e-69: 254: 29.69
+	Hs
		310030 TNKS1_HUMAN (12-400): 2.92e-79: 291: 16.63		TNKS1_HUMAN (1-334): 3.72e-67: 249: 29.17
+	Mm
		103591 ANK3_MOUSE (41-592): 7.79e-85: 311: 15.58		ANK3_MOUSE (746-1052): 3.19e-57: 218: 18.45