HitPredict

Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: WASF1 (Q8R5H6)
Actin-binding protein WASF1 (Protein WAVE-1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Gene: WASF1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	27507650, 28671696, 28701918, 28469556
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1730 Mm			1 559
+	Mm
		1115999 SHAN3_MOUSE (1-1730): 0: 626: 100.00		WASF2_MOUSE (1-541): 4.05e-60: 209: 42.33
+	Mm
		88456 SHAN3_MOUSE (1-1730): 0: 626: 100.00		D3Z656_MOUSE (123-557): 1.28e-32: 135: 13.97
+	Hs
		1127307 SHAN3_HUMAN (1-1730): 0: 601: 95.21		TGO1_HUMAN (133-489): 1.05e-25: 114: 16.30
+	Mm
		1116160 SHAN3_MOUSE (1-1730): 0: 626: 100.00		PCLO_MOUSE (56-547): 8.48e-09: 60.8: 12.41
+	Hs
		1127316 Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21		TGO1_HUMAN (133-489): 1.05e-25: 114: 16.30
+	Hs
		883527 RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21		TGO1_HUMAN (133-489): 1.05e-25: 114: 16.30
+	Hs
		556698 ANK1_HUMAN (175-669): 2.17e-43: 176: 15.35		EP300_HUMAN (78-554): 1.13e-28: 123: 15.74
+	Hs
		978563 ANKK1_HUMAN (181-522): 4.36e-61: 227: 19.88		PRB3_HUMAN (119-401): 2.02e-10: 64.7: 11.29
+	Dm
		113976 M9PB30_DROME (662-1371): 7.2e-27: 122: 15.27		M9PB30_DROME (74-554): 1.08e-09: 63.9: 9.65
+	Mm
		222869 ANK2_MOUSE (134-335): 6.85e-09: 63.5: 31.19		ACK1_MOUSE (251-500): 6.41e-20: 96.2: 21.01