Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: DLG2 (Q91XM9)
Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Gene: DLG2

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 27507650, 28671696, 29111324, 28469556
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~SH3_1, PDZ~PDZ_6, PDZ~SAM_1, Guanylate_kin~SH3_2, PDZ~SH3_2, SH3_1~SH3_2
Common GO terms GO:0014069 - postsynaptic density
GO:0043005 - neuron projection
GO:0044877 - protein-containing complex binding
GO:0045211 - postsynaptic membrane
GO:0098919 - structural constituent of postsynaptic density
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1730
Mm

1 852
+ Rn
+ Mm
+ Mm
+ Mm
+ Hs
+ Rn
+ Mm
+ Mm
+ Mm
+ Ce
+ Hs
+ Mm
+ Rn
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024