Interactor 1: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Interactor 2: MPP2 (Q9WV34)
MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2)
Gene: MPP2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 27507650, 28671696, 29111324
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~PDZ_6, PDZ~SAM_1, Guanylate_kin~SH3_2, PDZ~SH3_2, SH3_2~SH3_2
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0043197 - dendritic spine
GO:0060291 - long-term synaptic potentiation
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1730
Mm

1 552
+ Rn
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Mm
+ Rn
+ Rn
+ Hs
+ Mm

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Last updated: 15 Jul 2024