HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: SRP68 (Q9UHB9)
Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein)
Gene: SRP68

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	29845934, 35271311, 18281698
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 627
+	Hs
		403361 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		SRP68_HUMAN (1-627): 0: 838: 100.00
+	Hs
		1031487 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		SRP68_HUMAN (1-627): 0: 838: 100.00
+	Hs
		516727 PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29		SRP68_HUMAN (1-627): 0: 838: 100.00
+	Hs
		1316928 MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42		SRP68_HUMAN (1-627): 0: 838: 100.00
+	Hs
		1347043 RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84		SRP68_HUMAN (1-627): 0: 838: 100.00
+	Hs
		1162705 LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23		SRP68_HUMAN (1-627): 0: 838: 100.00
+	Sc
		704883 LHP1_YEAST (7-270): 1.34e-45: 163: 22.74		SRP68_YEAST (78-613): 1.02e-147: 442: 21.42