HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 582 Hs			1 559
+	Hs
		1054362 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		403362 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		PUF60_HUMAN (1-559): 2.1e-103: 324: 100.00
+	Hs
		1031490 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		PUF60_HUMAN (1-559): 2.1e-103: 324: 100.00
+	Hs
		1116304 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PAP1L_HUMAN (421-559): 9.16e-15: 79.2: 13.67
+	Hs
		1116542 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PABP3_HUMAN (479-559): 6.17e-13: 73.4: 19.75
+	Hs
		1031352 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516541 LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		403225 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1031328 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		1020249 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	At
		285478 LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20		PABP8_ARATH (470-559): 7.04e-20: 95.4: 15.56
+	At
		285476 LRP6B_ARATH (2-265): 6.42e-54: 194: 21.20		PABP2_ARATH (452-559): 1.38e-17: 88: 13.89
+	At
		790116 LRP6C_ARATH (12-249): 1.53e-49: 179: 23.14		PABP2_ARATH (452-559): 1.38e-17: 88: 13.89
+	Hs
		1031413 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		474021 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		PAB4L_HUMAN (479-559): 3.69e-14: 76.1: 20.99
+	Sc
		376709 LHP1_YEAST (7-270): 1.34e-45: 163: 22.74		PABP_YEAST (465-553): 7.06e-12: 69.9: 16.85
+	Hs
		403212 LA_HUMAN (24-365): 5.96e-44: 163: 18.83		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516689 PABP3_HUMAN (1-333): 6.27e-42: 162: 10.11		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		516495 PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		516568 LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64