HitPredict

Interactor 1: RD23B (Q4KMA2)
UV excision repair protein RAD23 homolog B
Gene: Rad23b

Interactor 2: Q5HZY3 (Q5HZY3)
Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12)
Gene: Uchl5

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19182904
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Peptidase_C12~ubiquitin, UCH_C~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070628 - proteasome binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 415 Rn			1 324
+	Hs
		872326 RD23B_HUMAN (1-415): 1.5e-116: 348: 86.51		UCHL5_HUMAN (1-316): 1.11e-168: 473: 97.15
+	Hs
		872237 RD23A_HUMAN (1-415): 2.25e-93: 287: 54.46		UCHL5_HUMAN (1-316): 1.11e-168: 473: 97.15
+	Hs
		1357351 UBQL1_HUMAN (1-410): 4.05e-64: 217: 13.60		UCHL5_HUMAN (1-316): 1.11e-168: 473: 97.15
+	Mm
		477056 UBC_MOUSE (1-110): 8.25e-31: 126: 23.64		UCHL5_MOUSE (1-316): 4.24e-170: 476: 99.05
+	Dm
		547969 RS27A_DROME (1-75): 4.56e-16: 76.9: 32.00		Q9XZ61_DROME (1-316): 1.03e-143: 409: 61.51
+	Hs
		548135 UBQL1_HUMAN (1-410): 4.05e-64: 217: 13.60		UCHL3_HUMAN (4-226): 2.46e-86: 260: 26.61
+	Hs
		872291 RD23B_HUMAN (1-415): 1.5e-116: 348: 86.51		BAP1_HUMAN (252-322): 4.71e-16: 80.9: 36.62
+	Dm
		547926 RS27A_DROME (1-75): 4.56e-16: 76.9: 32.00		CALYP_DROME (1-315): 9.78e-118: 349: 33.15
+	Mm
		477030 UBC_MOUSE (1-110): 8.25e-31: 126: 23.64		UCHL3_MOUSE (4-226): 1.44e-86: 261: 27.04
+	Hs
		474910 UBB_HUMAN (1-80): 5.99e-31: 120: 30.00		UCHL3_HUMAN (4-226): 2.46e-86: 260: 26.61
+	Hs
		548107 Q5U5U6_HUMAN (1-80): 5.99e-31: 120: 30.00		UCHL3_HUMAN (4-226): 2.46e-86: 260: 26.61
+	Mm
		476730 UBC_MOUSE (1-110): 8.25e-31: 126: 23.64		UCHL4_MOUSE (4-226): 5.85e-83: 252: 26.70
+	Hs
		456474 UBB_HUMAN (1-80): 5.99e-31: 120: 30.00		UCHL1_HUMAN (10-226): 1.42e-77: 238: 22.22
+	Mm
		477047 UBC_MOUSE (1-110): 8.25e-31: 126: 23.64		UCHL1_MOUSE (10-226): 2.06e-75: 232: 22.67
+	Hs
		548102 NEDD8_HUMAN (1-64): 8.1e-15: 71.1: 37.50		UCHL3_HUMAN (4-226): 2.46e-86: 260: 26.61
+	Sc
		477613 RL40A_YEAST (1-111): 3.39e-37: 133: 22.52		UBL1_YEAST (1-226): 8.76e-61: 195: 24.79
+	Hs
		456536 RS27A_HUMAN (1-91): 4.3e-16: 76.9: 26.37		UCHL1_HUMAN (10-226): 1.42e-77: 238: 22.22
+	Hs
		456575 NEDD8_HUMAN (1-64): 8.1e-15: 71.1: 37.50		UCHL1_HUMAN (10-226): 1.42e-77: 238: 22.22
+	Hs
		924096 RS27A_HUMAN (1-91): 4.3e-16: 76.9: 26.37		BAP1_HUMAN (252-322): 4.71e-16: 80.9: 36.62