HitPredict

Interactor 1: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	26186194, 33961781, 20972459
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0035329 - hippo signaling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1084 Hs			1 400
+	Mm
		1257594 AMOT_MOUSE (1-1084): 3.42e-87: 307: 75.11		WWTR1_MOUSE (1-400): 7.96e-120: 355: 91.00
+	Hs
		808669 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Mm
		809078 AMOT_MOUSE (1-1084): 3.42e-87: 307: 75.11		YAP1_MOUSE (15-400): 5.62e-100: 307: 41.30
+	Hs
		1119052 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		1119026 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		125503 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		1118983 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		1119055 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		SAV1_HUMAN (2-252): 3.57e-48: 169: 15.89
+	Hs
		1119035 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		MAGI1_HUMAN (10-212): 9.04e-40: 153: 15.74
+	Hs
		808761 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		808151 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		1119076 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Hs
		1119034 AMOT_HUMAN (1-1084): 2.27e-101: 346: 100.00		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Hs
		125569 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		1220065 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		1220103 MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92		KIBRA_HUMAN (123-265): 3.08e-45: 169: 18.88
+	Hs
		808183 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		1132674 FKB15_HUMAN (184-1080): 4.84e-41: 166: 14.92		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Hs
		1349059 MYH4_HUMAN (350-812): 1.95e-39: 162: 15.92		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Hs
		1222263 AMOL1_HUMAN (1-912): 6.22e-40: 162: 42.98		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20