HitPredict

Interactor 1: K9JA46 (K9JA46)
Heat shock protein HSP 90-alpha
Gene: EL52

Interactor 2: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	25036637
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	FKBP_C~HSP90
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Hs			1 457
+	Hs
		431818 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Hs
		111936 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59
+	Hs
		431755 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59
+	Mm
		432409 HS90A_MOUSE (1-732): 0: 1083: 97.82		FKBP4_MOUSE (1-444): 7.18e-136: 400: 55.38
+	Hs
		438089 HS90B_HUMAN (19-732): 0: 1059: 86.13		FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59
+	Hs
		111943 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBPL_HUMAN (133-414): 4.04e-51: 178: 25.70
+	Hs
		431781 HS90A_HUMAN (1-732): 0: 1087: 100.00		PPID_HUMAN (249-414): 4.11e-51: 178: 24.55
+	Hs
		432312 HS90A_HUMAN (1-732): 0: 1087: 100.00		AIPL1_HUMAN (125-419): 6.14e-51: 178: 19.89
+	Hs
		432338 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBPL_HUMAN (133-414): 4.04e-51: 178: 25.70
+	Hs
		111929 K9JA46_HUMAN (1-732): 0: 1087: 100.00		AIP_HUMAN (144-414): 1.52e-49: 173: 16.72
+	Hs
		118674 HS90A_HUMAN (1-732): 0: 1087: 100.00		AIP_HUMAN (144-414): 1.52e-49: 173: 16.72
+	Hs
		118678 HS90B_HUMAN (19-732): 0: 1059: 86.13		AIP_HUMAN (144-414): 1.52e-49: 173: 16.72
+	Hs
		111930 K9JA46_HUMAN (1-732): 0: 1087: 100.00		FKBP6_HUMAN (2-137): 2.27e-35: 135: 35.97
+	Hs
		259914 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP6_HUMAN (2-137): 2.27e-35: 135: 35.97
+	Hs
		431850 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKBP8_HUMAN (25-330): 3.36e-27: 114: 19.23
+	Hs
		259915 HS90B_HUMAN (19-732): 0: 1059: 86.13		FKBP6_HUMAN (2-137): 2.27e-35: 135: 35.97
+	Hs
		111934 K9JA46_HUMAN (1-732): 0: 1087: 100.00		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		431574 HS90A_HUMAN (1-732): 0: 1087: 100.00		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		431721 HS90A_HUMAN (1-732): 0: 1087: 100.00		FKB1A_HUMAN (151-247): 2.87e-21: 90.3: 26.73
+	Hs
		437930 HS90B_HUMAN (19-732): 0: 1059: 86.13		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62