HitPredict

Interactor 1: DDX17 (Q501J6)
Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17)
Gene: DDX17

Interactor 2: RNC (Q5HZJ0)
Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III)
Gene: Drosha

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	24581491
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	DEAD~Ribonuclease_3, Helicase_C~dsrm
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus GO:0005829 - cytosol GO:0006364 - rRNA processing GO:0010586 - miRNA metabolic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 650 Mm			1 1373
+	Hs
		1271678 DDX17_HUMAN (26-650): 0: 602: 98.88		RNC_HUMAN (1-1373): 0: 1315: 95.56
+	Hs
		571611 DDX5_HUMAN (3-637): 0: 532: 65.37		RNC_HUMAN (1-1373): 0: 1315: 95.56
+	Mm
		1126442 Q8BTS0_MOUSE (3-637): 0: 530: 65.27		RNC_MOUSE (1-1373): 0: 1313: 100.00
+	Hs
		1271697 DDX17_HUMAN (26-650): 0: 602: 98.88		DICER_HUMAN (1112-1196): 2.61e-11: 70.7: 31.46
+	Hs
		998944 DDX17_HUMAN (26-650): 0: 602: 98.88		EP300_HUMAN (13-371): 3.21e-11: 70.7: 10.50
+	Hs
		571417 DDX5_HUMAN (3-637): 0: 532: 65.37		EP300_HUMAN (13-371): 3.21e-11: 70.7: 10.50
+	Hs
		571635 DDX5_HUMAN (3-637): 0: 532: 65.37		DICER_HUMAN (1112-1196): 2.61e-11: 70.7: 31.46
+	Hs
		998860 DDX42_HUMAN (9-616): 2.38e-150: 460: 34.74		EP300_HUMAN (13-371): 3.21e-11: 70.7: 10.50
+	Hs
		134001 DDX3X_HUMAN (2-502): 1.65e-147: 444: 39.62		EP300_HUMAN (13-371): 3.21e-11: 70.7: 10.50
+	Hs
		998835 DDX46_HUMAN (47-472): 2.18e-107: 350: 43.38		EP300_HUMAN (13-371): 3.21e-11: 70.7: 10.50