Interactor 1: MBRL (Q4ZIN3)
Membralin (Transmembrane protein 259)
Gene: TMEM259

Interactor 2: RN185 (Q96GF1)
E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185)
Gene: RNF185

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.694

The method score is based on:

Property Details
Experiments 32738194, 32614325, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:1904294 - positive regulation of ERAD pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 620
Hs

1 192
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024