HitPredict

Interactor 1: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Interactor 2: DCNL1 (Q96GG9)
DCN1-like protein 1 (DCNL1) (DCUN1 domain-containing protein 1) (Defective in cullin neddylation protein 1-like protein 1) (Squamous cell carcinoma-related oncogene)
Gene: DCUN1D1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 568 Hs			1 259
+	Hs
		1292409 KLH20_HUMAN (2-566): 1.23e-174: 509: 43.94		DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00
+	Hs
		299530 KLH18_HUMAN (5-565): 1.58e-159: 469: 39.79		DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00
+	Hs
		1292397 KLHL8_HUMAN (5-565): 5.61e-156: 461: 37.41		DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00
+	Hs
		299519 KLH18_HUMAN (5-565): 1.58e-159: 469: 39.79		DCNL2_HUMAN (1-257): 3.46e-130: 370: 78.21
+	Hs
		1292400 KLH13_HUMAN (380-568): 2.64e-43: 165: 28.06		DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00
+	Hs
		1292398 KLHL9_HUMAN (380-568): 3.91e-43: 164: 27.55		DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00
+	Hs
		1121487 KLH26_HUMAN (365-568): 5.54e-30: 126: 23.26		DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00
+	Hs
		1161488 KLH24_HUMAN (394-568): 1.15e-28: 122: 29.67		DCNL2_HUMAN (1-257): 3.46e-130: 370: 78.21
+	Hs
		1292404 KLH21_HUMAN (427-553): 2.26e-10: 65.5: 35.39		DCNL1_HUMAN (1-259): 3.35e-134: 380: 100.00